ULK1

Gene Symbol ULK1
Entrez Gene 8408
Alt Symbol ATG1, ATG1A, UNC51, Unc51.1, hATG1
Species Human
Gene Type protein-coding
Description unc-51 like autophagy activating kinase 1
Other Description ATG1 autophagy related 1 homolog|autophagy-related protein 1 homolog|serine/threonine-protein kinase ULK1
Swissprots O75385 Q9UQ28
Accessions CBX47626 EAW98529 O75385 AB018265 BAA34442 AF045458 AAC32326 AK095774 AK128333 BC111603 AAI11604 BI822269 BU729635 CF131673 XM_011538798 XP_011537100 XM_011538799 XP_011537101 XR_944753 NM_003565 NP_003556
Function Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3- kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation. {ECO:0000269|PubMed:18936157, ECO:0000269|PubMed:21460634, ECO:0000269|PubMed:21795849}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Preautophagosomal structure {ECO:0000250}. Note=Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane that sequesters a portion of the cytoplasm resulting in the formation of an autophagosome. {ECO:0000250}.
Tissue Specificity Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung.
Top Pathways AMPK signaling pathway, Regulation of autophagy, mTOR signaling pathway

unc-51-like kinase 1 (C. elegans) , ELISA Kit - MBS9317785 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 5.0pg/ml.
Range 31.2pg/ml-1000pg/ml.

Human ULK1 ELISA Kit - E102154 from Biobool

Category ELISA Kit

anti-ATG1 / ULK1 antibody - ARG54811 from Arigo Biolaboratories

Category ELISA Kit

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9344555 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9355864 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9355313 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9366817 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9367913 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9368300 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9362567 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9357607 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9354657 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9346794 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9357222 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9346049 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9361590 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9345038 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ULK1 (Unc-51 Like Kinase 1), ELISA Kit - MBS7606854 from MyBioSource

Category ELISA Kit
Prices $295.00, $390.00, $1,615.00, $3,015.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 9.375pg/ml
Range 15.625-1000pg/ml

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9357678 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9359156 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9346612 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9354404 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Kinase ULK1 (ULK1), ELISA Kit - MBS9362505 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ULK1 ELISA Kit (Human ) (OKWB00203) - OKWB00203 from Aviva Systems Biology

Category ELISA Kit
Sensitivity 9.4 pg/mL
Range 15.625 - 1,000 pg/mL
Search more