Gene Symbol | Bin1 |
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Entrez Gene | 30948 |
Alt Symbol | ALP-1, Amphl, BRAMP-2, SH3P9 |
Species | Mouse |
Gene Type | protein-coding |
Description | bridging integrator 1 |
Other Description | SH3 domain-containing protein 9|amphiphysin 2|amphiphysin II|amphiphysin-like protein|myc box dependent interacting protein 1|myc box-dependent-interacting protein 1 |
Swissprots | Q62434 O08539 |
Accessions | EDK97060 EDK97061 O08539 AI840452 AK077987 BAC37090 AK184020 AK191982 AW496330 BC030446 BC065160 AAH65160 BQ573238 BU707946 CF732768 CJ121020 CO426739 U60884 AAC52661 XM_006525978 XP_006526041 XM_006525979 XP_006526042 XM_006525980 XP_006526043 XM_006525981 XP_006526044 XM_006525982 XP_006526045 XM_006525983 XP_006526046 XM_006525984 XP_006526047 XM_006525985 XP_006526048 XM_006525986 XP_006526049 XM_006525987 XP_006526050 XM_006525988 XP_006526051 XM_006525989 XP_006526052 XM_006525990 XP_006526053 XM_006525991 XP_006526054 XM_006525992 XP_006526055 XM_006525993 XP_006526056 XM_006525994 XP_006526057 XM_006525995 XP_006526058 NM_001083334 NP_001076803 NM_009668 NP_033798 |
Function | May be involved in regulation of synaptic vesicle endocytosis. May act as a tumor suppressor and inhibits malignant cell transformation. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Isoform 1 is expressed mainly in the brain. Isoform 2 is widely expressed. |
Amphiphysin II CRISPR/Cas9 KO Plasmid (m) - sc-424430 from Santa Cruz Biotechnology
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Amphiphysin II HDR Plasmid (m) - sc-424430-HDR from Santa Cruz Biotechnology
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Amphiphysin II Double Nickase Plasmid (m) - sc-424430-NIC from Santa Cruz Biotechnology
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Amphiphysin II Double Nickase Plasmid (m2) - sc-424430-NIC-2 from Santa Cruz Biotechnology
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Amphiphysin II CRISPR Activation Plasmid (m) - sc-424430-ACT from Santa Cruz Biotechnology
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Amphiphysin II CRISPR Activation Plasmid (m2) - sc-424430-ACT-2 from Santa Cruz Biotechnology
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Amphiphysin II Lentiviral Activation Particles (m) - sc-424430-LAC from Santa Cruz Biotechnology
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Amphiphysin II Lentiviral Activation Particles (m2) - sc-424430-LAC-2 from Santa Cruz Biotechnology
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Amphiphysin II siRNA (m) - sc-29805 from Santa Cruz Biotechnology
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Amphiphysin II shRNA Plasmid (m) - sc-29805-SH from Santa Cruz Biotechnology
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Amphiphysin II shRNA (m) Lentiviral Particles - sc-29805-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU018321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN27629 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND27629 from Sigma-Aldrich
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BIN1 siRNA (Mouse) - CRM5087 from Cohesion Biosciences
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BIN1 - MBS8227033 from MyBioSource
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shRNA set against Mouse BIN1 (NM_009668.2) - SHH246718 from Creative biogene
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shRNA set against Mouse Bin1(NM_009668.2) - SHG034507 from Creative biogene
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BIN1 shRNA Plasmid (Mouse) - CHM5087 from Cohesion Biosciences
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BIN1 miRNA 3'UTR clone - MiUTR1M-02206 from Creative biogene
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BIN1 miRNA 3'UTR clone - MiUTR1M-02207 from Creative biogene
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