BPTF

Gene Symbol BPTF
Entrez Gene 2186
Alt Symbol FAC1, FALZ, NURF301
Species Human
Gene Type protein-coding
Description bromodomain PHD finger transcription factor
Other Description bromodomain and PHD domain transcription factor|bromodomain and PHD finger-containing transcription factor|fetal Alz-50 clone 1 protein|fetal Alz-50 reactive clone 1|fetal Alzheimer antigen|nucleosome remodeling factor, large subunit|nucleosome-remodeling factor subunit BPTF
Swissprots Q6NX67 Q7Z7D6 Q12830 Q9UIG2
Accessions EAW89038 EAW89039 Q12830 AB032251 BAA89208 AK022081 AK022570 AK025776 AK027184 BAB15686 AK293224 BAG56763 AK296256 BAG58970 AK297281 BAG59752 AL833375 AY282495 AAP22284 BC037422 BC039881 BC050566 AAH50566 BC067234 AAH67234 BE464864 BQ716216 BU169920 BU176205 CF135401 CV809604 U05237 AAA97522 XM_005257150 XP_005257207 XM_005257151 XP_005257208 XM_005257152 XP_005257209 XM_005257153 XP_005257210 XM_005257154 XP_005257211 XM_005257155 XP_005257212 XM_005257156 XP_005257213 XM_005257157 XP_005257214 XM_005257158 XP_005257215 XM_005257159 XP_005257216 XM_005257160 XP_005257217 XM_005257161 XP_005257218 XM_005257162 XP_005257219 XM_011524520 XP_011522822 XM_011524521 XP_011522823 XM_011524522 XP_011522824 XM_011524523 XP_011522825 XM_011524524 XP_011522826 XM_011524525 XP_011522827 XM_011524526 XP_011522828 NM_004459 NP_004450 NM_182641 NP_872579
Function Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.
Subcellular Location Cytoplasm. Nucleus. Note=In brains of Alzheimer disease patients, present in a subset of amyloid- containing plaques.
Tissue Specificity Ubiquitously expressed, with highest levels in testis. Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex (at protein level). {ECO:0000269|PubMed:10662542, ECO:0000269|PubMed:10727212, ECO:0000269|PubMed:7621746, ECO:0000269|PubMed:9225734}.

BPTF CRISPR/Cas9 KO Plasmid (h) - sc-404092 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BPTF HDR Plasmid (h) - sc-404092-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BPTF Double Nickase Plasmid (h) - sc-404092-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BPTF Double Nickase Plasmid (h2) - sc-404092-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BPTF CRISPR Activation Plasmid (h) - sc-404092-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BPTF CRISPR Activation Plasmid (h2) - sc-404092-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BPTF Lentiviral Activation Particles (h) - sc-404092-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BPTF Lentiviral Activation Particles (h2) - sc-404092-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BPTF siRNA (h) - sc-93894 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BPTF shRNA Plasmid (h) - sc-93894-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BPTF shRNA (h) Lentiviral Particles - sc-93894-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BPTF/FALZ RNAi - H00002186-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU124831 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4041 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4041 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

BPTF siRNA (Human) - CRH1523 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BPTF/FALZ RNAi - H00002186-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

BPTF - MBS8206283 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Bptf (NM_182641.3) - SHH247506 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human BPTF(NM_004459.6) - SHG103789 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human BPTF(NM_182641.3) - SHG103825 from Creative biogene

Category siRNA
Species Reactivities Human

BPTF shRNA Plasmid (Human) - CHH1523 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

BPTF miRNA 3'UTR clone - MiUTR1H-00935 from Creative biogene

Species Reactivities Human

BPTF miRNA 3'UTR clone - MiUTR1H-00936 from Creative biogene

Species Reactivities Human
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