POLM

Gene Symbol POLM
Entrez Gene 27434
Alt Symbol Pol Mu, Tdt-N
Species Human
Gene Type protein-coding
Description polymerase (DNA directed), mu
Other Description DNA polymerase mu|DNA-directed DNA/RNA polymerase mu|Pol iota|polymerase (DNA-directed), mu|terminal transferase
Swissprots Q6P5X8 Q9NP87 Q86WQ9 D3DVK4
Accessions AAW65376 EAW61120 EAW61121 EAW61122 EAW61123 EAW61124 EAW61125 EAW61126 EAW61127 Q9NP87 AA917987 AF176097 AAF26284 AJ131891 CAB65075 AK023002 BAB14353 AK092801 AK092903 AK291638 BAF84327 AK294449 BAG57686 AK307634 AU309799 BC026306 AAH26306 BC035685 BC049202 AAH49202 BC062590 AAH62590 BI001584 DC407437 XM_005249711 XP_005249768 XM_006715692 XP_006715755 XM_006715693 XP_006715756 XM_006715696 XP_006715759 XM_006715697 XP_006715760 XM_006715698 XP_006715761 XM_011515275 XP_011513577 XM_011515276 XP_011513578 XM_011515277 XP_011513579 XM_011515278 XP_011513580 XM_011515279 XP_011513581 XM_011515280 XP_011513582 XM_011515281 XP_011513583 XM_011515282 XP_011513584 XM_011515283 XP_011513585 XM_011515284 XP_011513586 XM_011515285 XP_011513587 XM_011515286 XP_011513588 XM_011515287 XP_011513589 XR_926931 XR_926932 XR_926933 NM_001284330 NP_001271259 NM_001284331 NP_001271260 NM_013284 NP_037416 NR_104299
Function Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. {ECO:0000269|PubMed:12640116, ECO:0000269|PubMed:12888504, ECO:0000269|PubMed:17483519, ECO:0000269|PubMed:17915942}.
Subcellular Location Nucleus {ECO:0000250}.
Tissue Specificity Expressed in a number of tissues. Abundant in thymus.
Top Pathways Non-homologous end-joining

DNA pol μ (E-8) - sc-398666 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DNA pol μ (E-8): sc-398666. Western blot analysis of DNA pol μ expression in A-431 (A), Jurkat (B) and HeLa (C) nuclear extracts and Jurkat (D), HeLa (E) and JAR (F) whole cell lysates.

DNA Pol μ (C-15) - sc-27769 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DNA pol μ (C-15): sc-27769. Western blot analysis of DNA pol μ expression in Jurkat whole cell lysate.

DNA Pol μ (E-15) - sc-27768 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DNA pol μ (H-76) - sc-367749 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-DNA polymerase mu antibody - ab118890 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab118890, at 5 µg/ml, staining DNA polymerase mu in Formalin-fixed, Paraffin-embedded Human Kidney tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-DNA polymerase mu antibody - ab87141 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-DNA polymerase mu antibody (ab87141) at 1 µg/ml (in 5% skim milk / PBS buffer) + transfected 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-DNA polymerase mu antibody - ab3500 from Abcam

Prices $242.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DNA polymerase mu antibody (ab3500) at 1/500 dilutionLane 1 : HeLa nuclear lysateLane 2 : HeLa whole cell lysateLane 3 : A431 whole cell lysateLane 4 : Jurkat whole cell lysateLane 5 : HEK293 whole cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab6721) at 1/5000 dilutionPerformed under reducing conditions.Exposure time :  2 minutes

Anti-DNA polymerase mu antibody [EPR10470(B)] - ab157465 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10470(B)
All lanes : Anti-DNA polymerase mu antibody [EPR10470(B)] (ab157465) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : HeLa cell lysateLane 3 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-POLM / DNA Polymerase Mu Antibody (C-Terminus) - LS-C102575 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
POLM antibody LS-C102575 Western blot of Transfected 293T cell lysate.

Anti-POLM / DNA Polymerase Mu Antibody (aa6-18) IHC-plus™ - LS-B406 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-POLM antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B406 concentration 5 ug/ml.

DNA polymerase mu Antibody - NBP1-58202 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DNA polymerase mu Antibody [NBP1-58202] - Titration: 0.2-1 ug/ml, Positive Control: Transfected 293T.

DNA polymerase mu Antibody - NBP2-16189 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DNA polymerase mu Antibody - NB120-3500 from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

DNA polymerase mu Polyclonal Antibody - bs-13021R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DNA polymerase mu Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13021R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DNA polymerase mu Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13021R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DNA polymerase mu Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13021R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DNA polymerase mu Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13021R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DNA polymerase mu Polyclonal Antibody, Cy3 Conjugated - bs-13021R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DNA polymerase mu Polyclonal Antibody, Cy5 Conjugated - bs-13021R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DNA polymerase mu Polyclonal Antibody, Cy5.5 Conjugated - bs-13021R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DNA polymerase mu Polyclonal Antibody, Cy7 Conjugated - bs-13021R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DNA polymerase mu Polyclonal Antibody, FITC Conjugated - bs-13021R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DNA polymerase mu Polyclonal Antibody, Biotin Conjugated - bs-13021R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DNA polymerase mu Polyclonal Antibody, HRP Conjugated - bs-13021R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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