MYC

Gene Symbol MYC
Entrez Gene 4609
Alt Symbol MRTL, MYCC, bHLHe39, c-Myc
Species Human
Gene Type protein-coding
Description v-myc avian myelocytomatosis viral oncogene homolog
Other Description avian myelocytomatosis viral oncogene homolog|class E basic helix-loop-helix protein 39|myc proto-oncogene protein|myc-related translation/localization regulatory factor|proto-oncogene c-Myc|transcription factor p64|v-myc myelocytomatosis viral oncogene homolog
Swissprots Q14026 P01107 A8WFE7 P01106
Accessions AAA59880 AAA59881 AAA59882 AAA59884 AAA59886 AAA59887 AAA88090 AAO21131 AAO31951 ABW69847 BAA01374 BAA01375 CAA25015 CAA25095 CAA25105 CAA25106 CAA25288 CAC22425 CAL18306 CAL18307 CAL18308 CAL18309 CAL18310 CAL18311 CAL18312 CAL18313 CAL18314 CAL18315 CAL18316 CAL18317 CAL18318 CAL18319 CAL18320 CAL18321 CAL18322 CAL18323 CAL18324 CAL18325 CAL18326 CAL18327 CAL18328 CAL18329 CAL18330 CAL18331 CAL18332 CAL18333 CAL18334 CAL18335 CAL18336 CAL18337 CAL18338 CAL18340 CAL18341 CAL18342 CAL18343 CAL18344 CAL18345 CAL18346 CAL18347 CAL18348 CAL18349 CAL18350 CAL18351 CAL18352 CAL18353 CAL18354 CAL18355 CAL18356 CAL18357 CAL18358 CAL18359 CAL18360 CAL18361 CAL18362 CAL18363 CAL18364 CAL18365 CAL18366 CAL18367 CAL18368 CAL18369 CAL18370 CAL18371 CAL18372 CAL18373 CAL18374 CAL18375 CAL18376 CAL18377 CAL18378 CAL18379 CAL18380 CAL18619 CAL18620 CAL18621 CAL18622 CAL18623 CAL18624 CAM91152 CAN37626 CBI12209 CBX47660 CBX54352 CCW44111 CDI30193 EAW92098 EAW92099 EAW92100 EAW92101 P01106 AA807892 AK303921 BAG64849 AK312883 BAG35731 BC000141 AAH00141 BC000917 AAH00917 BC058901 AAH58901 BG499628 BK006467 DAA06340 BT019768 AAV38573 DQ894085 ABM85011 K02276 AAA36340 KC782559 AGV06354 M13929 AAA88091 M13930 AAA88093 V00568 CAA23831 X66258 CAA46984 NM_002467 NP_002458
Function Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes.
Subcellular Location Nucleus, nucleoplasm {ECO:0000269|PubMed:17558397}. Nucleus, nucleolus {ECO:0000269|PubMed:17558397}.
Top Pathways MicroRNAs in cancer, Wnt signaling pathway, Central carbon metabolism in cancer, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway

SignalSilence ® c-Myc siRNA II - 6552 from Cell Signaling Technology

Category siRNA
Prices $256.00
Sizes 300 µl (3 nmol)
Species Reactivities Human
Western blot analysis of extracts from HeLa cells, transfected with 100 nM SignalSilence ® Control siRNA (Fluorescein Conjugate) #6201 (-) or SignalSilence ® c-Myc siRNA II (+), using c-Myc Antibody #9402 and β-Actin (13E5) Rabbit mAb #4970. c-Myc Antibody confirms silencing of c-Myc expression and β-Actin (13E5) Rabbit mAb is used to control for loading and specificity of c-Myc siRNA.

SignalSilence ® c-Myc siRNA I - 6341 from Cell Signaling Technology

Category siRNA
Prices $256.00
Sizes 300 µl (50-100 transfections)
Species Reactivities Human
Western blot analysis of extracts from HeLa cells following mock transfection, transfection with nonspecific (control) siRNA or transfection with SignalSilence ® c-Myc siRNA I, using c-Myc Antibody #9402 and p42 MAP Kinase (Erk2) Antibody #9108. The c-Myc antibody confirms silencing of c-Myc expression and the p42 MAPK antibody is used to control for loading and specificity of c-Myc siRNA.

c-Myc CRISPR/Cas9 KO Plasmid (h) - sc-400001 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Myc HDR Plasmid (h) - sc-400001-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Myc Double Nickase Plasmid (h) - sc-400001-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Myc Double Nickase Plasmid (h2) - sc-400001-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Myc CRISPR Activation Plasmid (h) - sc-400001-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Myc CRISPR Activation Plasmid (h2) - sc-400001-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Myc Lentiviral Activation Particles (h) - sc-400001-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Myc Lentiviral Activation Particles (h2) - sc-400001-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Myc siRNA (h) - sc-29226 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

c-Myc shRNA Plasmid (h) - sc-29226-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

c-Myc shRNA (h) Lentiviral Particles - sc-29226-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

c-Myc siRNA (h2) - sc-44248 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

c-Myc shRNA Plasmid (h2) - sc-44248-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

c-Myc shRNA (h2) Lentiviral Particles - sc-44248-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

c-Myc RNAi - H00004609-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU021051 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1041 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04687 from Sigma-Aldrich

Category miRNA

MYC siRNA (Human) - CRH3040 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MYC (NM_002467.4) - SHH347524 from Creative biogene

Category siRNA
Species Reactivities Human

MYC shRNA Plasmid (Human) - CHH3040 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MYC miRNA 3'UTR clone - MiUTR3H-02272 from Creative biogene

Species Reactivities Human
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