| Gene Symbol |
ADAMTS5
|
| Entrez Gene |
286805
|
| Alt Symbol |
-
|
| Species |
Bovine
|
| Gene Type |
protein-coding
|
| Description |
ADAM metallopeptidase with thrombospondin type 1 motif, 5
|
| Other Description |
A disintegrin and metalloproteinase with thrombospondin motifs 5|ADAM-TS 5|ADAM-TS5|ADAMTS-5|ADMP-2|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5|aggrecanase-2
|
| Swissprots |
Q9TT92
|
| Accessions |
DAA33657 Q9TT92 AF192771 AAF07177 XM_010800929 XP_010799231 NM_001166515 NP_001159987
|
| Function |
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000250}.
|
