| Gene Symbol | sev |
|---|---|
| Entrez Gene | 32039 |
| Alt Symbol | 7LES, 7less, CG18085, CT3980, DROSEV, DROSEV1, DmHD-265, Dmel\CG18085, HD-265, SEV, Sev, sev(AC)[[14]] |
| Species | Drosophila |
| Gene Type | protein-coding |
| Description | sevenless |
| Other Description | CG18085-PA|sev-PA |
| Swissprots | Q9VZ36 P13368 Q9U5V7 Q9TYI0 |
| Accessions | AAF47992 NM_078559 NP_511114 |
| Function | Receptor for an extracellular signal required to instruct a cell to differentiate into an R7 photoreceptor. The ligand for sev is the boss (bride of sevenless) protein on the surface of the neighboring R8 cell. {ECO:0000269|PubMed:2840202}. |
| Subcellular Location | Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Top Pathways | MAPK signaling pathway - fly |
sevenless (dR-15) - sc-15742 from Santa Cruz Biotechnology
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