VPS26A

Gene Symbol	VPS26A
Entrez Gene	9559
Alt Symbol	HB58, Hbeta58, PEP8A, VPS26
Species	Human
Gene Type	protein-coding
Description	vacuolar protein sorting 26 homolog A (S. pombe)
Other Description	vacuolar protein sorting-associated protein 26A|vesicle protein sorting 26A
Swissprots	O75436 Q9H982 B2RDD3 Q8TBH4 A8MZ56
Accessions	EAW54311 EAW54312 EAW54313 O75436 AF054179 AAC39912 AF175266 AAF89954 AK022992 BAB14351 AK290536 BAF83225 AK297142 BAG59643 AK309021 AK315496 BAG37880 AL110166 BC022505 AAH22505 BQ048905 BX647725 BX649092 CD358963 EU832481 ACE87653 EU832561 ACE86963 XM_011540378 XP_011538680 NM_001035260 NP_001030337 NM_004896 NP_004887
Function	Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins (Probable). The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5 (Probable). Required for retrograde transport of lysosomal enzyme re
Subcellular Location	Cytoplasm. Endosome membrane; Peripheral membrane protein. Early endosome {ECO:0000269|PubMed:15078903}. Note=Localizes to tubular profiles adjacent to endosomes (PubMed:15078903). Predominantly found in early not late endosomes (By similarity). {ECO:0000250|UniProtKB:P40336}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human VPS26 full length protein - ab130047 from Abcam Category Protein Source E. coli Species Human

Human VPS26 full length protein - ab132016 from Abcam Category Protein Source Wheat germ Species Human

Human VPS26 peptide - ab24288 from Abcam Category Peptide

Human VPS26 peptide - ab23150 from Abcam Category Peptide Species Human

VPS26A / VPS26 Antibody Blocking Peptide - LS-E25672 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

VPS26A / VPS26 Antibody Blocking Peptide - LS-E22521 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

VPS26A / VPS26 Antibody Blocking Peptide - LS-E9745 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

VPS26 Partial Recombinant Protein - H00009559-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

VPS26 Recombinant Protein - H00009559-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human VPS26 Protein - NBP1-98890 from Novus Biologicals Category Protein Prices $269.00 Sizes 20 µg Source E. coli Species Human

VPS26A-Antibody-Center-Blocking-Peptide - BP8722c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

VPS26A blocking peptide - GTX26051-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Pig, Rat, Bovine

Human VPS26A protein - orb169550 from Biorbyt Category Protein Prices $230.00, $442.00, $1,811.00 Sizes 2 μg, 10 μg, 100 μg Source E.coli Species Human

Goat anti VPS26A antibody Immunizing peptide - orb17848 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

VPS26A Blocking Peptide - 33R-5503 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

VPS26A protein (His tag) - 80R-2385 from Fitzgerald Category Protein Prices $270.00 Sizes 20 µg Source E.coli

VPS26 Peptide - AC21-0502-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

VPS26A (1-327, His-tag) - AR50466PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

VPS26A (1-327, His-tag) - AR50466PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

VPS26A - H00009559-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

VPS26A - H00009559-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

VPS26A - H00009559-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

VPS26A - H00009559-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

VPS26A, 1-327aa, Human, His tag, E.coli - 01-P1642 from ARP American Research Products Category Protein Prices $139.00, $369.00, $849.00 Sizes 5 µg, 20 µg, 100 µg Species Human

VPS26A Peptide - 46-579P from ProSci Category Peptide Species Human

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