POLR2G

Gene Symbol POLR2G
Entrez Gene 5436
Alt Symbol RPB19, RPB7, hRPB19, hsRPB7
Species Human
Gene Type protein-coding
Description polymerase (RNA) II (DNA directed) polypeptide G
Other Description DNA directed RNA polymerase II 19 kda polypeptide|DNA-directed RNA polymerase II 19 kDa polypeptide|DNA-directed RNA polymerase II subunit G|DNA-directed RNA polymerase II subunit RPB7|RNA polymerase II 19 kDa subunit|RNA polymerase II seventh subunit|RNA polymerase II subunit B7
Swissprots B2R5C0 Q2M1Z4 P62487
Accessions AAB96827 EAW74090 EAW74091 EAW74092 P62487 AK312131 BAG35067 AW016747 BC112162 AAI12163 BC112164 AAI12165 BG530809 U20659 AAA86500 NM_002696 NP_002687
Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity). Binds RNA. {ECO:0000250, ECO:0000269|PubMed:9852112}.
Subcellular Location Nucleus {ECO:0000269|PubMed:9852112}.
Top Pathways Huntington's disease, Epstein-Barr virus infection, Purine metabolism, RNA polymerase, Pyrimidine metabolism

POLR2G (2781C2a) - sc-81112 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
POLR2G (2781C2a): sc-81112 Western Blot analysis of POLR2G expression in F2408 whole cell lysate.

POLR2G (C-2) - sc-398213 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
POLR2G (C-2): sc-398213. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.

POLR2G (FL-172) - sc-367151 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

POLR2G (G-9) - sc-393890 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
POLR2G (G-9): sc-393890. Western blot analysis of POLR2G expression in HT-1080 (A), NIH/3T3 (B), A-431 (C) and Jurkat (D) whole cell lysates.

POLR2G (S-12) - sc-131333 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-POLR2G antibody - ab96031 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-POLR2G antibody (ab96031) at 1/1000 dilution + A431 whole cell lysate at 30 µg

Anti-POLR2G antibody - ab172095 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-POLR2G antibody (ab172095) at 1/500 dilutionLane 1 : Lysate from 293T cells transfected with POLR2GLane 2 : Lysate from untransfected 293T cellsLysates/proteins at 15 µl per lane.

Anti-POLR2G antibody [2781C2a] - ab53742 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2781C2a
Anti-POLR2G antibody [2781C2a] (ab53742) at 1/50 dilution + NIH3T3 whole cell lysate at 25 µgSecondaryanti-mouse IgG at 1/2500 dilutiondeveloped using the ECL technique

Anti-POLR2G antibody - C-terminal - ab170847 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Flow cytometric analysis of Jurkat cells labeling POLR2G using ab170847 at a 1/10 dilution (right histogram), compared to negative control cells (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Anti-POLR2G antibody - C-terminal - ab156377 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-POLR2G antibody - C-terminal (ab156377) at 1/100 dilution + A375 cell lysate at 35 µg

Anti-POLR2G / RPB7 Antibody - LS-C75505 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-POLR2G / RPB7 Antibody (aa118-129) - LS-C108125 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-POLR2G / RPB7 Antibody (aa126-153, AP) - LS-C223708 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2G / RPB7 Antibody (aa126-153, Biotin) - LS-C223710 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2G / RPB7 Antibody (aa126-153, APC) - LS-C223709 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2G / RPB7 Antibody (aa126-153, FITC) - LS-C223711 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2G / RPB7 Antibody (aa126-153, Azide-free, HRP) - LS-C223712 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2G / RPB7 Antibody (aa126-153, PE) - LS-C223713 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2G / RPB7 Antibody (aa125-154, AP) - LS-C223714 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2G / RPB7 Antibody (aa125-154, APC) - LS-C223715 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2G / RPB7 Antibody (aa125-154, Biotin) - LS-C223716 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2G / RPB7 Antibody (aa125-154, FITC) - LS-C223717 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2G / RPB7 Antibody (aa125-154, Azide-free, HRP) - LS-C223718 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2G / RPB7 Antibody (aa125-154, PE) - LS-C223720 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR2G / RPB7 Antibody (aa145-153) - LS-C324170 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more