BMPR1A

Gene Symbol BMPR1A
Entrez Gene 657
Alt Symbol 10q23del, ACVRLK3, ALK3, CD292, SKR5
Species Human
Gene Type protein-coding
Description bone morphogenetic protein receptor, type IA
Other Description ALK-3|BMP type-1A receptor|BMPR-1A|activin A receptor, type II-like kinase 3|activin receptor-like kinase 3|bone morphogenetic protein receptor type-1A|serine/threonine-protein kinase receptor R5
Swissprots Q8NEN8 A8K6U9 P36894
Accessions CBY84973 EAW80320 P36894 AB451405 BAG70219 AK291764 BAF84453 BC028383 AAH28383 BM819272 DQ786215 DQ891524 ABM82450 DQ894714 ABM85640 Z22535 CAA80257 XM_011540103 XP_011538405 XM_011540104 XP_011538406 NM_004329 NP_004320
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Highly expressed in skeletal muscle.
Top Pathways Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells

Active human BMPR1A (mutated R486 Q) protein fragment - ab201403 from Abcam

Category Protein
Prices $294.00
Sizes 5 µg
Source Baculovirus infected sf9 cells
Species Human
ab201403 activity assay with or without TGFBR1 peptide substrate. ab201403 did not show significant kinase activity in vitro.

Active human BMPR1A protein fragment - ab105907 from Abcam

Category Protein
Prices $302.00, $352.00, $1,845.00
Sizes 5 µg, 10 µg, 100 µg
Source Baculovirus infected sf9 cells
Species Human
Kinase Assay demonstrating specific activity of ab105907 at 1.2 nmol/min/mg.

Active human BMPR1A protein fragment - ab123844 from Abcam

Category Protein
Prices $410.00
Sizes 10 µg
Source Baculovirus infected insect cells
Species Human

Active human BMPR1A protein fragment - ab201369 from Abcam

Category Protein
Prices $294.00
Sizes 5 µg
Source Baculovirus infected sf9 cells
Species Human
SDS-PAGE analysis of ab201369

Active human BMPR1A protein fragment - ab157350 from Abcam

Category Protein
Prices $352.00
Sizes 200 µg
Source HEK 293 cells
Species Human
SDS-PAGE analysis of reduced ab157350 stained overnight with Coomassie Blue.

Human BMPR1A full length protein - ab131986 from Abcam

Category Protein
Prices $402.00
Sizes 10 µg
Source Wheat germ
Species Human
12.5% SDS-PAGE, stained with Coomassie Blue showing ab131986.

Human BMPR1A protein fragment - ab157341 from Abcam

Category Protein
Prices $297.00
Sizes 200 µg
Source HEK 293 cells
Species Human
SDS-PAGE analysis of reduced ab157341 stained overnight with Coomassie Blue.

Human BMPR1A protein fragment - ab157970 from Abcam

Category Protein
Prices $402.00
Sizes 10 µg
Source Wheat germ
Species Human
ab157970 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human BMPR1A protein fragment - ab185408 from Abcam

Category Protein
Prices $147.00
Sizes 10 µg
Source Mammalian
Species Human

Human BMPR1A protein fragment - ab55202 from Abcam

Category Protein
Prices $438.00
Sizes 100 µg
Source Insect cells
Species Human

ALK3 / BMPR1A Antibody Blocking Peptide - LS-E4217 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ALK3 / BMPR1A Antibody Blocking Peptide - LS-E6792 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ALK3 / BMPR1A Antibody Blocking Peptide - LS-E6793 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ALK3 / BMPR1A Antibody Blocking Peptide - LS-E6794 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ALK3 / BMPR1A Antibody Blocking Peptide - LS-E6795 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ALK3 / BMPR1A Antibody Blocking Peptide - LS-E6796 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ALK3 / BMPR1A Antibody Blocking Peptide - LS-E26072 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

BMPR-IA/ALK-3 Recombinant Protein - H00000657-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

BMPR-IA/ALK-3 Partial Recombinant Protein - H00000657-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

BMPR-IA/ALK-3 Recombinant Protein - P4155 from Novus Biologicals

Category Protein
Prices $799.00
Sizes 10 µg
Species Human

BMPR-IA/ALK-3 Protein - NBP1-99582 from Novus Biologicals

Category Protein
Prices $399.00
Sizes 10 µg
Species Human

BMPR-IA/ALK-3 Recombinant Protein - H00000657-G01 from Novus Biologicals

Category Protein
Prices $579.00
Sizes 10 µg
Species Human

BMPR-IA/ALK-3 Peptide - P0793 from Novus Biologicals

Category Peptide
Species Human

BMPR-IA/ALK-3 Peptide - P0792 from Novus Biologicals

Category Peptide
Species Human

BMPR-IA/ALK-3 Peptide - P0791 from Novus Biologicals

Category Peptide
Species Human
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