| Gene Symbol | Osm |
|---|---|
| Entrez Gene | 18413 |
| Alt Symbol | OncoM |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | oncostatin M |
| Other Description | oncostatin-M |
| Swissprots | Q3U1Y5 P53347 Q5SPX6 |
| Accessions | EDL40468 EDL40469 P53347 AK087945 BAC40053 AK155637 BAE33358 BC099866 AAH99866 XM_011243671 XP_011241973 NM_001013365 NP_001013383 |
| Function | Growth regulator. Inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells (By similarity). Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity). {ECO:0000250}. |
| Subcellular Location | Secreted. |
| Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, PI3K-Akt signaling pathway |
Mouse Oncostatin M / OSM HEK293 Cell Lysate (WB positive control) - 50112-M08HL-300 from Sino Biological
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Mouse Oncostatin M Human Cells Transfected Lysate (positive control) (denatured) - orb174042 from Biorbyt
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