| Gene Symbol |
Atad5
|
| Entrez Gene |
237877
|
| Alt Symbol |
C130052G03Rik, FRAG1, Gm17
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
ATPase family, AAA domain containing 5
|
| Other Description |
ATPase family AAA domain-containing protein 5|chromosome fragility associated gene 1|chromosome fragility-associated gene 1 protein
|
| Swissprots |
Q3UW85 Q3V3T9 Q4QY64 Q8BUH4 Q8CGG7 Q5SSK4 Q3V306 Q3TMG5
|
| Accessions |
EDL15623 Q4QY64 AK032814 BAE20483 AK048355 AK053857 BAE20694 AK079959 AK085211 BAC39389 AK136531 BAE23031 AK165945 BAE38477 AY557610 AAT52048 BC038279 AAH38279 BC046463 BC141180 AAI41181 BC160289 AAI60289 XM_006533232 XP_006533295 XM_006533233 XP_006533296 XM_006533234 XP_006533297 XM_011248989 XP_011247291 NM_001029856 NP_001025027
|
| Function |
Involved in DNA damage response. Involved in a RAD9A- related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages- induced apoptosis. {ECO:0000269|PubMed:15983387}.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
| Tissue Specificity |
Expressed ubiquitously in all cell lines like teratocarcinoma, cell lymphoma, lymphoma. {ECO:0000269|PubMed:15983387}.
|