Gene Symbol |
Kcp
|
Entrez Gene |
333088
|
Alt Symbol |
AW060220, CRIM-2, Crim2, Gm793, KCP-1
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
kielin/chordin-like protein
|
Other Description |
cysteine rich BMP regulator 2 (chordin like)|cysteine-rich BMP regulator 2|cysteine-rich motor neuron 2 protein|kielin/chordin-like protein 1
|
Swissprots |
Q3U492 E9QJU0 Q56NI8
|
Accessions |
Q3U492 AK154369 BAE32541 AK160694 AY884211 AAX77677 BC032979 BC059023 BC059909 AAH59909 BC119794 BQ179923 CB524845 CJ103176 CN691587 XM_006505131 XP_006505194 XM_006505134 XP_006505197 XM_011241070 XP_011239372 XM_011241071 XP_011239373 XM_011241072 XP_011239374 XR_868759 XR_868760 XR_868761 XR_868762 NM_001029985 NP_001025156
|
Function |
Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. In contrast, it inhibits both the activin-A and TGFB1-mediated signaling pathways. {ECO:0000269|PubMed:15793581}.
|
Subcellular Location |
Secreted {ECO:0000269|PubMed:15793581}.
|
Tissue Specificity |
Weakly expressed in embryonic kidney and brain. Not expressed in adult tissues and several cell lines. {ECO:0000269|PubMed:15793581}.
|