Gene Symbol | Hmga2 |
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Entrez Gene | 15364 |
Alt Symbol | 9430083A20Rik, HMGI-C, Hmgic, pg, pygmy |
Species | Mouse |
Gene Type | protein-coding |
Description | high mobility group AT-hook 2 |
Other Description | high mobility group AT-hook protein 2|high mobility group protein HMGI-C|high mobility group protein I |
Swissprots | P52927 Q3UQW0 |
Accessions | AAC69244 CAA68187 EDL24402 P52927 AK028346 BAC25896 AK035164 AK142059 BAE24928 AK144714 AK147859 BC052158 AAH52158 BC069985 AAH69985 BC085085 AAH85085 BY013519 CJ173998 X58380 CAA41270 XM_006513251 XP_006513314 XM_011243374 XP_011241676 NM_010441 NP_034571 |
Function | Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. {ECO:0000269|PubMed:14668482}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:14668482}. |
Tissue Specificity | Expressed in mitotic spermatogonia, meiotic spermatocytes, and postmeiotic round spermatids (at protein level). {ECO:0000269|PubMed:14668482}. |
Top Pathways | MicroRNAs in cancer, Transcriptional misregulation in cancer |
HMGI-C CRISPR/Cas9 KO Plasmid (m) - sc-420880 from Santa Cruz Biotechnology
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HMGI-C HDR Plasmid (m) - sc-420880-HDR from Santa Cruz Biotechnology
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HMGI-C Double Nickase Plasmid (m) - sc-420880-NIC from Santa Cruz Biotechnology
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HMGI-C Double Nickase Plasmid (m2) - sc-420880-NIC-2 from Santa Cruz Biotechnology
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HMGI-C CRISPR Activation Plasmid (m) - sc-420880-ACT from Santa Cruz Biotechnology
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HMGI-C CRISPR Activation Plasmid (m2) - sc-420880-ACT-2 from Santa Cruz Biotechnology
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HMGI-C Lentiviral Activation Particles (m) - sc-420880-LAC from Santa Cruz Biotechnology
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HMGI-C Lentiviral Activation Particles (m2) - sc-420880-LAC-2 from Santa Cruz Biotechnology
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HMGI-C siRNA (m) - sc-37995 from Santa Cruz Biotechnology
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HMGI-C shRNA Plasmid (m) - sc-37995-SH from Santa Cruz Biotechnology
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HMGI-C shRNA (m) Lentiviral Particles - sc-37995-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU196671 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN33335 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33335 from Sigma-Aldrich
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HMGA2 siRNA (Mouse) - CRM1852 from Cohesion Biosciences
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HMGA2 - MBS8229522 from MyBioSource
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shRNA set against Mouse Hmga2 (NM_010441.2) - SHH313281 from Creative biogene
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shRNA set against Mouse Hmga2(NM_010441.2) - SHH124975 from Creative biogene
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Mouse HMGA2 siRNA - orb281328 from Biorbyt
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HMGA2 shRNA Plasmid (Mouse) - CHM1852 from Cohesion Biosciences
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HMGA2 miRNA 3'UTR clone - MiUTR1M-05694 from Creative biogene
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