CD200R1

Gene Symbol CD200R1
Entrez Gene 131450
Alt Symbol CD200R, HCRTR2, MOX2R, OX2R
Species Human
Gene Type protein-coding
Description CD200 receptor 1
Other Description CD200 cell surface glycoprotein receptor|MOX2 receptor|cell surface glycoprotein CD200 receptor 1|cell surface glycoprotein OX2 receptor 1|cell surface glycoprotein receptor CD200
Swissprots Q6IS95 Q6UW94 Q8TD52 E9PCM9 Q8TD46 Q8TD44 Q8TD45 B3KWZ9 Q52LJ7 Q6WHB8
Accessions CCF77016 CCF77017 CCF77018 CCF77019 EAW79657 EAW79658 EAW79659 EAW79660 EAW79661 Q8TD46 AF283760 AAN61171 AF495380 AAM14622 AF497548 AAM16157 AF497549 AAM16158 AF497550 AAM16159 AK126349 BAG54311 AK293071 BAF85760 AK304426 BAG65254 AY284975 AAQ19772 AY358910 AAQ89269 BC069661 AAH69661 BC069721 AAH69721 BC069743 AAH69743 BC093890 AAH93890 BC143393 AAI43394 HQ447427 ADQ31913 XM_006713492 XP_006713555 NM_138806 NP_620161 NM_138939 NP_620385 NM_138940 NP_620386 NM_170780 NP_740750
Function Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. {ECO:0000269|PubMed:12960329}.
Subcellular Location Isoform 2: Secreted.
Tissue Specificity Expressed in granulocytes, monocytes, most T- cells, neutrophils, basophils and a subset of NK, NKT and B-cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells. {ECO:0000269|PubMed:12960329}.

OX2R CRISPR/Cas9 KO Plasmid (h) - sc-404121 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OX2R HDR Plasmid (h) - sc-404121-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OX2R Double Nickase Plasmid (h) - sc-404121-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OX2R Double Nickase Plasmid (h2) - sc-404121-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OX2R CRISPR Activation Plasmid (h) - sc-404121-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OX2R CRISPR Activation Plasmid (h2) - sc-404121-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OX2R Lentiviral Activation Particles (h) - sc-404121-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OX2R Lentiviral Activation Particles (h2) - sc-404121-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OX2R siRNA (h) - sc-42956 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OX2R shRNA Plasmid (h) - sc-42956-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OX2R shRNA (h) Lentiviral Particles - sc-42956-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Orexin R2/HCRTR2 RNAi - H00003062-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: Orexin R2/HCRTR2 RNAi [H00003062-R01V] - Analysis of HCRTR2 over-expressed 293 cell line, cotransfected with HCRTR2 Validated Chimera RNAi or non-transfected control. Blot probed with H00003062-M01. GAPDH (36.1 kDa) used as loading control.

CD200 R1 RNAi - H00131450-R07 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CD200 R1 RNAi - H00131450-R06 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Orexin R2/HCRTR2 RNAi - H00003062-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU113831 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5696 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5696 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07724 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07724

CD200R1 siRNA (Human) - CRJ5064 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CD200 R1 RNAi - H00131450-R05 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CD200 R1 RNAi - H00131450-R08 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CD200R1 - MBS8208131 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CD200R1 (NM_138806.3) - SHH258645 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CD200R1(NM_138940.2) - SHG155323 from Creative biogene

Category siRNA
Species Reactivities Human
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