| Gene Symbol |
Degs1
|
| Entrez Gene |
13244
|
| Alt Symbol |
AA536663, Degs, Des1, Mdes
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
degenerative spermatocyte homolog 1 (Drosophila)
|
| Other Description |
dihydroceramide desaturase|sphingolipid delta(4)-desaturase DES1
|
| Swissprots |
Q8R4H3 O09005
|
| Accessions |
EDL13111 O09005 AF466376 AAM12532 AK002617 BAB22233 AK077257 BAC36713 AK149811 BAE29098 AK150908 AK163404 BAE37337 AK165352 BC003751 AAH03751 Y08460 CAA69714 NM_007853 NP_031879
|
| Function |
Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). {ECO:0000269|PubMed:11937514}.
|
| Subcellular Location |
Mitochondrion. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Detected in testis. Detected in pachytene spermatocytes and round spermatids. {ECO:0000269|PubMed:9227906}.
|
| Top Pathways |
Sphingolipid signaling pathway, Sphingolipid metabolism
|