TAS1R1

Gene Symbol TAS1R1
Entrez Gene 80835
Alt Symbol GM148, GPR70, T1R1, TR1
Species Human
Gene Type protein-coding
Description taste receptor, type 1, member 1
Other Description G protein-coupled receptor 70|G-protein coupled receptor 70|seven transmembrane helix receptor|taste receptor type 1 member 1
Swissprots Q8TDJ7 Q5SY24 Q7RTX1 Q8NGZ7 Q8TDK0 B2RMX0 Q5SY22 Q8TDJ8 Q8TDJ9
Accessions BAC05845 CAJ58406 CAJ58407 CAJ58408 CAJ58409 EAW71551 EAW71552 EAW71553 EAW71554 Q7RTX1 AF387617 AAL91358 AF387618 AAL91359 AF387619 AAL91360 AF387620 AAL91361 AI742401 AK292014 BAF84703 AK293499 BAG56985 AK315805 BAG38146 BC136515 AAI36516 BC136516 AAI36517 BK000153 DAA00012 CA426652 XM_011542202 XP_011540504 XM_011542203 XP_011540505 XM_011542204 XP_011540506 XM_011542205 XP_011540507 XM_011542206 XP_011540508 NM_138697 NP_619642 NM_177540 NP_803884 NM_177539 NM_177541
Function Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. {ECO:0000269|PubMed:11917125}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Top Pathways Taste transduction

T1R1 (C-20) - sc-22451 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

T1R1 (H-120) - sc-50307 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

T1R1 (L-20) - sc-34049 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-GPCR TAS1R1 antibody - ab79248 from Abcam

Host Rabbit
Clonality Polyclonal
ICC/IF image of ab79248 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab79248, 1/200 dilution) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-GPCR TAS1R1 antibody - ab79260 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-GPCR TAS1R1 antibody - ab65416 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-GPCR TAS1R1 antibody - ab129691 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-GPCR TAS1R1 antibody (ab129691) at 1/100 dilution + A375 cell line lysates at 35 µg

Anti-GPCR TAS1R1 antibody - N-terminal - ab155143 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-GPCR TAS1R1 antibody - N-terminal (ab155143) at 1/1000 dilution + NT2D1 whole cell lysate at 30 µg

Anti-GPCR TAS1R1 antibody - N-terminal - ab150535 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue labelling GPCR TAS1R1 with ab150535 at 5µg/ml.

Anti-T1R1 / TAS1R1 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A1994 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-T1R1 / TAS1R1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-T1R1 / TAS1R1 Antibody (aa323-351, Biotin) - LS-C241540 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-T1R1 / TAS1R1 Antibody (aa323-351, APC) - LS-C241539 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-T1R1 / TAS1R1 Antibody (aa323-351, FITC) - LS-C241541 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-T1R1 / TAS1R1 Antibody (aa323-351, PE) - LS-C241542 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-T1R1 / TAS1R1 Antibody (aa323-351, Azide-free, HRP) - LS-C248308 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-T1R1 / TAS1R1 Antibody (aa323-351, AP) - LS-C241538 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-T1R1 / TAS1R1 Antibody (aa322-351) - LS-C325575 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-T1R1 / TAS1R1 Antibody (aa223-272) - LS-C187348 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human HepG2. TAS1R1 antibody dilution 1.0 ug/ml.

Anti-T1R1 / TAS1R1 Antibody (aa327-376) - LS-C169768 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-T1R1 / TAS1R1 Antibody (aa323-351) - LS-C161708 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TAS1R1 Antibody western blot of A375 cell line lysates (35 ug/lane). The TAS1R1 antibody detected the TAS1R1 protein (arrow).

Anti-T1R1 / TAS1R1 Antibody (N-Terminus) IHC-plus™ - LS-A1992 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-T1R1 / TAS1R1 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-T1R1 / TAS1R1 Antibody (C-Terminus) - LS-C39500 from LifeSpan Bioscience

Prices $415.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-T1R1 / TAS1R1 Antibody (C-Terminus) - LS-C39501 from LifeSpan Bioscience

Prices $415.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

TAS1R1 Antibody - NBP2-20571 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TAS1R1 Antibody [NBP2-20571] - Sample (30 ug of whole cell lysate) A: NT2D1 7. 5% SDS PAGE gel, diluted at 1:1000.

TAS1R1 Antibody - NBP1-83338 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TAS1R1 Antibody [NBP1-83338] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp
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