CYP2A13

Gene Symbol CYP2A13
Entrez Gene 1553
Alt Symbol CPAD, CYP2A, CYPIIA13
Species Human
Gene Type protein-coding
Description cytochrome P450, family 2, subfamily A, polypeptide 13
Other Description cytochrome P450 2A13|cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 13
Swissprots Q6R569 Q16696 Q9H2X2 Q6R570 Q53YR8
Accessions AAB40519 EAW57016 Q16696 AF209774 AAG35775 AY513604 AAR90935 AY513605 AAR90936 AY513606 AAR90937 AY513607 AAR90938 AY513608 AAR90939 AY513609 AAR90940 BC148422 AAI48423 BC153000 AAI53001 BM975825 NM_000766 NP_000757
Function Exhibits a coumarin 7-hydroxylase activity. Active in the metabolic activation of hexamethylphosphoramide, N,N- dimethylaniline, 2'-methoxyacetophenone, N- nitrosomethylphenylamine, and the tobacco-specific carcinogen, 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanone. Possesses phenacetin O-deethylation activity. {ECO:0000269|PubMed:18779312}.
Subcellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue Specificity Expressed in liver and a number of extrahepatic tissues, including nasal mucosa, lung, trachea, brain, mammary gland, prostate, testis, and uterus, but not in heart, kidney, bone marrow, colon, small intestine, spleen, stomach, thymus, or skeletal muscle. {ECO:0000269|PubMed:11016631}.
Top Pathways Chemical carcinogenesis, Metabolism of xenobiotics by cytochrome P450

CYP2A13 293T Cell Transient Overexpression Lysate(Denatured) - H00001553-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

CYP2A (h): 293T Lysate - sc-128391 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

CYP2A13 Overexpression Lysate (Denatured) - H00001553-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human CYP2A13 Knockdown Stable Cell Line - CSC-DC003952 from Creative biogene

Category Cell Line
Species Human
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