BAK1

Gene Symbol BAK1
Entrez Gene 578
Alt Symbol BAK, BAK-LIKE, BCL2L7, CDN1
Species Human
Gene Type protein-coding
Description BCL2-antagonist/killer 1
Other Description BCL2-like 7 protein|apoptosis regulator BAK|bcl-2 homologous antagonist/killer|bcl-2-like protein 7|bcl2-L-7|pro-apoptotic protein BAK
Swissprots Q16611 C0H5Y7 Q6I9T6 Q92533
Accessions AAO74828 BAA13606 EAX03740 EAX03741 EAX03742 Q16611 AF520590 AAM74949 AK091807 BAG52419 AK292093 BAF84782 AK293547 BAG57025 AK303422 BAG64474 BC004431 AAH04431 BC032789 BC110337 AAI10338 BM855203 CB142221 CR457419 CAG33700 CR627020 CAI46254 DQ892527 ABM83453 DQ895739 ABM86665 U16811 AAA74466 U23765 AAA93066 X84213 CAA58997 XM_011514779 XP_011513081 XM_011514780 XP_011513082 NM_001188 NP_001179
Function In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis. {ECO:0000269|PubMed:17157251, ECO:0000269|PubMed:8521816}.
Subcellular Location Mitochondrion membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
Top Pathways Protein processing in endoplasmic reticulum, Viral carcinogenesis, MicroRNAs in cancer

SignalSilence ® Bak siRNA I - 6486 from Cell Signaling Technology

Category siRNA
Prices $256.00
Sizes 300 µl (3 nmol)
Species Reactivities Human
Western blot analysis of extracts from OVCAR8 cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-) or SignalSilence ® Bak siRNA I (+), using Bak (D2D3) Rabbit mAb #6947 (upper) or α-Tubulin (11H10) Rabbit mAb #2125 (lower). The Bak (D2D3) Rabbit mAb confirms silencing of Bak expression, while the α-Tubulin (11H10) Rabbit mAb is used as a loading control.

Bak CRISPR/Cas9 KO Plasmid (h) - sc-400646 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bak HDR Plasmid (h) - sc-400646-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bak Double Nickase Plasmid (h) - sc-400646-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bak Double Nickase Plasmid (h2) - sc-400646-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bak CRISPR Activation Plasmid (h) - sc-400646-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bak CRISPR Activation Plasmid (h2) - sc-400646-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bak Lentiviral Activation Particles (h) - sc-400646-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bak Lentiviral Activation Particles (h2) - sc-400646-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Bak siRNA (h) - sc-29786 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Bak shRNA Plasmid (h) - sc-29786-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Bak shRNA (h) Lentiviral Particles - sc-29786-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU106501 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU113511 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1956 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1956 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

BAK1 siRNA (Human) - CRH0396 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BAK1 - MBS8214587 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human BAK1 (NM_001188.3) - SHH244794 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human BAK1(NM_001188.3) - SHG091015 from Creative biogene

Category siRNA
Species Reactivities Human

Human BAK1 siRNA - orb260898 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BAK1 shRNA Plasmid (Human) - CHH0396 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

BAK1 miRNA 3'UTR clone - MiUTR1H-00799 from Creative biogene

Species Reactivities Human
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