HNRNPA1

Gene Symbol HNRNPA1
Entrez Gene 3178
Alt Symbol ALS19, ALS20, HNRPA1, HNRPA1L3, IBMPFD3, hnRNP A1, hnRNP-A1
Species Human
Gene Type protein-coding
Description heterogeneous nuclear ribonucleoprotein A1
Other Description Putative heterogeneous nuclear ribonucleoprotein A1-like 3|helix-destabilizing protein|heterogeneous nuclear ribonucleoprotein A1B protein|heterogeneous nuclear ribonucleoprotein B2 protein|heterogeneous nuclear ribonucleoprotein core protein A1|hnRNP A1-like 3|hnRNP core protein A1|hnRNP core protein A1-like 3|nuclear ribonucleoprotein particle A1 protein|single-strand DNA-binding protein UP1|single-strand RNA-binding protein
Swissprots Q6PJZ7 P09651 A8K4Z8 Q3MIB7
Accessions CAA31191 EAW96761 EAW96762 EAW96763 EAW96764 EAW96765 EAW96766 EAW96767 EAW96768 EAW96769 EAW96770 P09651 AK129814 AK291113 BAF83802 AK298176 BAG60447 AK303303 BAG64377 AK308679 BC002355 AAH02355 BC004945 AAH04945 BC009600 AAH09600 BC012158 AAH12158 BC020442 BC033714 AAH33714 BC035253 BC052296 AAH52296 BC070315 AAH70315 BC071945 AAH71945 BC073162 AAH73162 BC074502 AAH74502 BC078165 BC103707 AAI03708 BC104236 AAI04237 BC104237 AAI04238 BC121133 AAI21134 BQ277208 BU501222 BX425482 CD705336 CF541085 U00947 X04347 CAA27874 X06747 CAA29922 X79536 CAA56072 XM_005268826 XP_005268883 XR_245923 XR_245924 NM_002136 NP_002127 NM_031157 NP_112420
Function Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication. {ECO:0000269|PubMed:17229681}.
Subcellular Location Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Shuttles continuously between the nucleus and the cytoplasm along with mRNA. Component of ribonucleosomes. In the course of viral infection, colocalizes with HCV NS5B at speckles in the cytoplasm in a HCV-replication dependent manner.
Top Pathways Spliceosome

hnRNP A1 (D21H11) Rabbit mAb - 8443 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D21H11
Western blot analysis of extracts from various cell lines using hnRNP A1 (D21H11) Rabbit mAb.

hnRNP A1 (R196) Antibody - 5380 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa and 293T cells using hnRNP A1 (R196) Antibody.

hnRNP A1 (K350) Antibody - 4296 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa and 293T cells using hnRNP A1 (K350) Antibody.

hnRNP A1 (D-4) - sc-374526 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
hnRNP A1 (D-4): sc-374526. Immunofluorescence staining of methanol-fixed HeLa cells showing nucleolar and nuclear localization.

hnRNP A1 (4B10) - sc-32301 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
hnRNP A1 (4B10): sc-32301. Western blot analysis of hnRNP A1 expression in non-transfected: sc-117752 (A) and human hnRNP A1 transfected: sc-114969 (B) 293T whole cell lysates.

hnRNP A1 (F-8) - sc-365486 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
hnRNP A1 (F-8): sc-365486: Western blot analysis of hnRNP A1 expression in non-transfected HEK 293T (A) and puromycin treated, hnRNP A1 CRISPR/Cas9 KO Plasmid (h): sc-400704 plus hnRNP A1 HDR Plasmid (h): sc-400704-HDR co-transfected HEK 293T (B) whole cell lysates. β-Actin (C4): sc-47778 used as specificity and loading control.

hnRNP A1 (N-15) - sc-10029 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
hnRNP A1 (N-15): sc-10029. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear staining.

hnRNP A1 (Y-15) - sc-10032 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
hnRNP A1 (Y-15): sc-10032. Western blot analysis of hnRNP A1 expression in K-562 (A) and KNRK (B) nuclear extracts.

hnRNP A1 (E-17) - sc-10030 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
hnRNP A1 (E-17): sc-10030: Western blot analysis of hnRNP A1 expression in non-transfected HEK 293T (A) and puromycin treated, hnRNP A1 CRISPR/Cas9 KO Plasmid (h): sc-400704 plus hnRNP A1 HDR Plasmid (h): sc-400704-HDR co-transfected HEK 293T (B) whole cell lysates. β-Actin (C4): sc-47778 used as specificity and loading control.

hnRNP A1 (C-2) - sc-166511 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
hnRNP A1 (C-2): sc-166511. Western blot analysis of hnRNP A1 expression in HeLa nuclear extract.

hnRNP A1 (9H10) - sc-56700 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
hnRNP A1 (9H10): sc-56700. Western blot analysis of hnRNP A1 expression in HeLa (A), MCF7 (B), K-562 (C) and SW480 (D) nuclear extracts and Jurkat (E) and HeLa (F) whole cell lysates.

Anti-hnRNP A1 (isoform A1-A) antibody - ab123378 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-hnRNP A1 (isoform A1-A) antibody (ab123378) at 1/500 dilution + 293 cell extract

Anti-hnRNP A1 antibody - ab4791 from Abcam

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-hnRNP A1 antibody (ab4791) at 1/500 dilutionLane 1 : HeLa Whole Cell ExtractLane 2 : HeLa Nuclear ExtractSecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab6721) at 1/2000 dilution

Anti-hnRNP A1 antibody - ab137780 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-hnRNP A1 antibody (ab137780) at 1/500 dilutionLane 1 : H1299 whole cell lysateLane 2 : HelaS3 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-hnRNP A1 antibody - ab50492 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human heart tissue labelling hnRNP A1 with ab50492 at 4.0-8.0µg/ml. Positive staining shown in cardiac cell. Magnification: 400X.

Anti-hnRNP A1 antibody - ab66893 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung tissue labelling hnRNP A1 with ab66893 at 4.0-8.0µg/ml. Positive staining shown in alveolar cells. Magnification: 400X.

Anti-hnRNP A1 antibody - ab131138 from Abcam

Prices $384.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of Formalin-Fixed, Paraffin-Embedded Human small intestine tissue labelling hnRNP A1 (isoform A1-A) with ab131138 at 5 µg/ml.

Anti-hnRNP A1 antibody [9H10] - ab5832 from Abcam

Prices $404.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 9H10
ab5832 at 1/2000 staining GM10725 cells (Lymphoblastoid cell line). The cells were paraformaldehyde fixed and blocked with BSA prior to incubation with the antibody for 12 hours. An Alexa-Fluor ® 594 conjugated donkey anti-mouse antibody was used as the secondary. Cells were mounted in DAPI and observed using a confocal microscope.See Abreview

Anti-hnRNP A1 antibody [EPR12768] - ab177152 from Abcam

Prices $99.00
Sizes 10 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12768
All lanes : Anti-hnRNP A1 antibody [EPR12768] (ab177152) at 1/1000 dilutionLane 1 : MCF7 cell lysateLane 2 : HepG2 cell lysateLane 3 : K562 cell lysateLane 4 : HeLa cell lysateLane 5 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-hnRNP A1 antibody [EPR12768] (Alexa Fluor® 488) - ab197852 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12768
ab197852 staining hnRNP A1 in HepG2 cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1%PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab197852 at a 1/100 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at a 1/250 dilution (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).This product also gave a positive signal under the same testing conditions in HepG2 cells fixed with 4% formaldehyde (10 min).

Anti-hnRNP A1 antibody [EPR12768] (Alexa Fluor® 647) - ab197854 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12768
ab197854 staining hnRNP A1 in HepG2 cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1%PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab197854 at a 1/100 dilution (shown in red) and ab195887, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 488), at a 1/250 dilution (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).This product also gave a positive signal under the same testing conditions in HepG2 cells fixed with 4% formaldehyde (10 min).

Anti-hnRNP A1 antibody [EPR12768] (HRP) - ab198535 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12768
All lanes : Anti-hnRNP A1 antibody [EPR12768] (HRP) (ab198535) at 1/5000 dilutionLane 1 : MCF-7 (Human breast adenocarcinoma cell line) Whole Cell LysateLane 2 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLane 3 : K562 (Human erythromyeloblastoid leukemia cell line) Whole Cell LysateLane 4 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate (ab150035)Lane 5 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.developed using the ECL techniquePerformed under reducing conditions.

Anti-HNRPA1 / HnRNP A1 Antibody - LS-C68185 from LifeSpan Bioscience

Prices $485.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal

Anti-HNRPA1 / HnRNP A1 Antibody (clone 9H10) - LS-C82262 from LifeSpan Bioscience

Prices $380.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 9H10

Anti-HNRPA1 / HnRNP A1 Antibody (clone 9H10) - LS-C82220 from LifeSpan Bioscience

Prices $450.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 9H10
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-hnRNP A1 antibody [9H10] staining human lung. Staining is localized to the nucleus.
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