| Gene Symbol |
Dpm2
|
| Entrez Gene |
13481
|
| Alt Symbol |
AW557993, R75484
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
dolichol-phosphate (beta-D) mannosyltransferase 2
|
| Other Description |
DPM synthase subunit 2|dolichol phosphate-mannose biosynthesis regulatory protein|dolichol-phosphate mannose synthase subunit 2
|
| Swissprots |
Q9Z324
|
| Accessions |
EDL08553 Q9Z324 AB013360 BAA33973 AK002468 BAB22122 AK004241 BAB23234 AK086634 AK179411 BC008256 AAH08256 NM_010073 NP_034203
|
| Function |
Regulates the biosynthesis of dolichol phosphate- mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Multi-pass membrane protein.
|
| Top Pathways |
N-Glycan biosynthesis, Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
|