ACSL6

Gene Symbol	ACSL6
Entrez Gene	23305
Alt Symbol	ACS2, FACL6, LACS 6, LACS2, LACS5
Species	Human
Gene Type	protein-coding
Description	acyl-CoA synthetase long-chain family member 6
Other Description	fatty-acid-Coenzyme A ligase, long-chain 6|long fatty acyl-CoA synthetase 2|long-chain-fatty-acid--CoA ligase 6
Swissprots	Q9UKU0 J3KPG3 O94924 Q86TN7 Q108N0 O95829 Q4G191 Q108M9
Accessions	EAW62355 EAW62356 EAW62357 EAW62358 EAW62359 EAW62360 Q9UKU0 AB020644 BAA74860 AF102845 AF129166 AAD47199 AK122702 BAG53676 AK294291 BAG57574 AK314452 BAG37060 AW952652 BC026161 AAH26161 BC047453 AAH47453 BI464352 BI545119 BI548729 BM992189 DA200154 DA801862 DB461818 DQ083030 AAZ30713 DQ083031 AAZ30714 DQ655980 JF432422 ADZ15639 NM_001009185 NP_001009185 NM_001205247 NP_001192176 NM_001205248 NP_001192177 NM_001205250 NP_001192179 NM_001205251 NP_001192180 NM_015256 NP_056071
Function	Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.
Subcellular Location	Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Peroxisome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
Tissue Specificity	Expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, hemopoietic stem cells from cord blood, bone marrow and brain. {ECO:0000269|PubMed:10548543}.
Top Pathways	Adipocytokine signaling pathway, PPAR signaling pathway, Peroxisome, Fatty acid biosynthesis, Fatty acid degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ACSL6 full length protein - ab161598 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

ACSL6 Antibody Blocking Peptide - LS-E6998 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ACSL6 Protein - H00023305-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ACSL6 Peptide - P1154 from Novus Biologicals Category Peptide Species Human

ACSL6 Peptide - P1153 from Novus Biologicals Category Peptide Species Human

FACL6-Antibody-Center-Blocking-Peptide - BP2537b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FACL6-Antibody-N-term-Blocking-Peptide - BP2537a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ACSL6 fusion protein - ag5002 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

ACSL6 fusion protein - Ag4817 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

ACSL6 Blocking Peptide - CBP3397 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

ACSL6 (D531) Peptide - BS3140P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Long-chain-fatty-acid--CoA ligase 6(ACSL6) - CSB-YP892139HU CSB-EP892139HU CSB-BP892139HU CSB-MP892139HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ACSL6 Protein - abx163989 from Abbexa Category Protein Species Human

ACSL6 (transcript variant 2) - TP311883 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ACSL6 (transcript variant 1) - TP316974 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ACSL6 Recombinant Protein Antigen - NBP1-89269PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ACSL6 Blocking Peptide - abx162259 from Abbexa Category Peptide Species Human, Mouse, Rat

ACSL6 Peptide, Human - M34GP00173H from Creative Peptides Category Peptide Source Synthetic. Species Human

Long-chain-fatty-acid--CoA ligase 6 (ACSL6), Recombinant Protein - MBS1395617 from MyBioSource Category Protein Prices $1,450.00, $1,450.00, $1,680.00, $1,680.00, $2,465.00, $2,465.00, $2,910.00, $2,910.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ACSL6 Peptide - orb224283 from Biorbyt Category Peptide Species Human, Mouse, Rat

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