GRM4

Gene Symbol GRM4
Entrez Gene 2914
Alt Symbol GPRC1D, MGLUR4, mGlu4
Species Human
Gene Type protein-coding
Description glutamate receptor, metabotropic 4
Other Description metabotropic glutamate receptor 4
Swissprots Q6ZMQ2 F5GXM5 B3KVL9 B7Z1U6 Q14833 Q5SZ84 B7Z1T9
Accessions AAB34891 EAX03759 EAX03760 Q14833 AA993227 AB209104 BAD92341 AK122836 BAG53752 AK122982 BAG53831 AK126746 BAG54370 AK131536 BAD18673 AK289524 BAF82213 AK289534 BAF82223 AK289563 BAF82252 AK293913 BAH11625 AK293949 BAH11632 AK308669 AK312300 BC130526 AAI30527 BC130528 AAI30529 BC144057 AAI44058 BM683737 DA094245 DA096351 DA116042 DA121890 EU432124 ABY87923 HQ258665 ADR83416 HQ258669 ADR83420 U92457 AAB51762 X80818 CAA56784 XM_011514531 XP_011512833 NM_000841 NP_000832 NM_001256809 NP_001243738 NM_001256811 NP_001243740 NM_001256812 NP_001243741 NM_001256813 NP_001243742 NM_001282847 NP_001269776 NM_001256810 NM_001256814
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. {ECO:0000269|PubMed:7617140, ECO:0000269|PubMed:8738157, ECO:0000269|PubMed:9473604}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:7617140, ECO:0000269|PubMed:8738157}; Multi-pass membrane protein {ECO:0000269|PubMed:7617140, ECO:0000269|PubMed:8738157}.
Tissue Specificity Strongly expressed in the cerebellum. Expressed at low levels in hippocampus, hypothalamus and thalamus. No expression detected in liver. {ECO:0000269|PubMed:7617140, ECO:0000269|PubMed:8738157}.
Top Pathways Taste transduction, Glutamatergic synapse, Neuroactive ligand-receptor interaction

mGluR-4 CRISPR/Cas9 KO Plasmid (h) - sc-404894 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-4 HDR Plasmid (h) - sc-404894-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-4 Double Nickase Plasmid (h) - sc-404894-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-4 Double Nickase Plasmid (h2) - sc-404894-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-4 CRISPR Activation Plasmid (h) - sc-404894-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-4 CRISPR Activation Plasmid (h2) - sc-404894-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-4 Lentiviral Activation Particles (h) - sc-404894-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-4 Lentiviral Activation Particles (h2) - sc-404894-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-4 siRNA (h) - sc-61032 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

mGluR-4 shRNA Plasmid (h) - sc-61032-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

mGluR-4 shRNA (h) Lentiviral Particles - sc-61032-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

mGluR4 RNAi - H00002914-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU016841 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9704 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9704 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GRM4 siRNA (Human) - CRH1967 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GRM4 - MBS8218267 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GRM4 (NM_000841.2) - SHH308126 from Creative biogene

Category siRNA
Species Reactivities Human

GRM4 shRNA Plasmid (Human) - CHH1967 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GRM4 miRNA 3'UTR clone - MiUTR3H-06542 from Creative biogene

Species Reactivities Human
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