PLCB3

Gene Symbol PLCB3
Entrez Gene 5331
Alt Symbol -
Species Human
Gene Type protein-coding
Description phospholipase C, beta 3 (phosphatidylinositol-specific)
Other Description 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3|PLC beta 3|PLC-beta-3|phosphoinositide phospholipase C-beta-3
Swissprots G5E960 A5PKZ6 Q8N1A4 Q01970
Accessions AAA77683 CAA85776 CBF62886 CBF74559 CBU87762 CBU96709 EAW74230 EAW74231 Q01970 AB385031 BAG10887 BC032659 AAH32659 BC041625 BC142681 AAI42682 BC146645 Z16411 CAA78903 Z26649 XM_005274052 XP_005274109 XM_011545101 XP_011543403 NM_000932 NP_000923 NM_001184883 NP_001171812
Function The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Subcellular Location Membrane; Peripheral membrane protein.
Top Pathways Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway, Thyroid hormone synthesis, Estrogen signaling pathway, Inflammatory mediator regulation of TRP channels