| Gene Symbol |
PLCB3
|
| Entrez Gene |
5331
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
| Other Description |
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3|PLC beta 3|PLC-beta-3|phosphoinositide phospholipase C-beta-3
|
| Swissprots |
G5E960 A5PKZ6 Q8N1A4 Q01970
|
| Accessions |
AAA77683 CAA85776 CBF62886 CBF74559 CBU87762 CBU96709 EAW74230 EAW74231 Q01970 AB385031 BAG10887 BC032659 AAH32659 BC041625 BC142681 AAI42682 BC146645 Z16411 CAA78903 Z26649 XM_005274052 XP_005274109 XM_011545101 XP_011543403 NM_000932 NP_000923 NM_001184883 NP_001171812
|
| Function |
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
|
| Subcellular Location |
Membrane; Peripheral membrane protein.
|
| Top Pathways |
Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway, Thyroid hormone synthesis, Estrogen signaling pathway, Inflammatory mediator regulation of TRP channels
|