Acaca

Gene Symbol Acaca
Entrez Gene 107476
Alt Symbol A530025K05Rik, Acac, Acc1, Gm738
Species Mouse
Gene Type protein-coding
Description acetyl-Coenzyme A carboxylase alpha
Other Description ACC-alpha|acaca|acetyl-CoA carboxylase 1|acetyl-CoA carboxylase 265
Swissprots Q6PHL9 Q5SWU8 Q91VC8 Q925C4 Q6JIZ1 Q5SWU9 Q705X8 A2A6H4 Q925C5 Q705X9 Q5SWU7 Q5SWU6
Accessions CAF02252 EDL15735 Q5SWU9 AF289714 AAG01858 AF374167 AAK57389 AF374168 AAK57390 AF374169 AAK57391 AF374170 AAK57392 AJ619664 CAF02251 AK040794 AK040962 AK047036 AK132628 AK144072 AY451393 AAS13685 BC023946 BC042725 BC049923 BC056500 AAH56500 BC064472 BC156144 AAI56145 BC156982 AAI56983 BY726813 CF745722 CN538919 CN705188 XM_006531953 XP_006532016 XM_006531954 XP_006532017 XM_006531955 XP_006532018 XM_006531956 XP_006532019 XM_006531957 XP_006532020 XM_006531958 XP_006532021 XM_011248666 XP_011246968 XM_011248667 XP_011246969 NM_133360 NP_579938
Function Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. {ECO:0000250|UniProtKB:Q13085}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12360400, ECO:0000269|PubMed:20952656}.
Top Pathways Insulin signaling pathway, AMPK signaling pathway, Glucagon signaling pathway, Fatty acid biosynthesis, Pyruvate metabolism

SignalSilence ® Acetyl-CoA Carboxylase 1 siRNA I (Mouse Specific) - 6397 from Cell Signaling Technology

Category siRNA
Prices $249.00
Sizes 300 µl (3 nmol)
Western blot analysis of extracts from NIH/3T3 cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® Acetyl-CoA Carboxylase 1 siRNA I (Mouse Specific) (+) or SignalSilence ® Acetyl-CoA Carboxylase 1 siRNA II (Mouse Specific) #6398 (+), using Acetyl-CoA Carboxylase 1 Antibody #4190 (upper) or α-Tubulin (11H10) Rabbit mAb #2125 (lower). The Acetyl-CoA Carboxylase 1 Antibody confirms silencing of Acetyl-CoA Carboxylase 1 expression, while the α-Tubulin (11H10) Rabbit mAb is used as a loading control.

SignalSilence ® Acetyl-CoA Carboxylase 1 siRNA II (Mouse Specific) - 6398 from Cell Signaling Technology

Category siRNA
Prices $249.00
Sizes 300 µl (3 nmol)
Western blot analysis of extracts from NIH/3T3 cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® Acetyl-CoA Carboxylase 1 siRNA I #6397 (Mouse Specific) (+), or SignalSilence ® Acetyl-CoA Carboxylase 1 siRNA II (Mouse Specific) (+), using Acetyl-CoA Carboxylase 1 Antibody #4190 (upper) or α-Tubulin (11H10) Rabbit mAb #2125 (lower). The Acetyl-CoA Carboxylase 1 Antibody confirms silencing of Acetyl-CoA Carboxylase 1 expression, while the α-Tubulin (11H10) Rabbit mAb is used as a loading control.

ACCα CRISPR/Cas9 KO Plasmid (m) - sc-430719 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACCα HDR Plasmid (m) - sc-430719-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACCα Double Nickase Plasmid (m) - sc-430719-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACCα Double Nickase Plasmid (m2) - sc-430719-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACCα CRISPR Activation Plasmid (m) - sc-430719-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACCα CRISPR Activation Plasmid (m2) - sc-430719-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACCα Lentiviral Activation Particles (m) - sc-430719-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACCα Lentiviral Activation Particles (m2) - sc-430719-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

ACCα siRNA (m) - sc-40313 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

ACCα shRNA Plasmid (m) - sc-40313-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

ACCα shRNA (m) Lentiviral Particles - sc-40313-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU213921 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN26111 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26111 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ACACA siRNA (Mouse) - CRN0830 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

ACACA - MBS8240837 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse ACACA (NM_133360.2) - SHH229846 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Acaca(NM_133360.2) - SHG027541 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse ACACA siRNA - orb290305 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

ACACA shRNA Plasmid (Mouse) - CHN0830 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

ACACA miRNA 3'UTR clone - MiUTR1M-01092 from Creative biogene

Species Reactivities Mouse
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