| Gene Symbol |
SRP14
|
| Entrez Gene |
6727
|
| Alt Symbol |
ALURBP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
signal recognition particle 14kDa (homologous Alu RNA binding protein)
|
| Other Description |
18 kDa Alu RNA-binding protein|signal recognition particle 14 kDa protein
|
| Swissprots |
Q6B0K5 B5BUF5 P37108 Q96Q14
|
| Accessions |
EAW92390 EAW92391 P37108 AB061546 BAB69067 AB451391 BAG70205 BC035495 AAH35495 BC051006 BC071716 AAH71716 BC100031 AAI00032 CV575824 HQ447734 ADQ32219 U07857 AAA59066 X73459 CAA51838 NM_003134 NP_003125 NR_104021
|
| Function |
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
|
| Subcellular Location |
Cytoplasm.
|
| Top Pathways |
Protein export
|