| Gene Symbol |
FMO1
|
| Entrez Gene |
2326
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
flavin containing monooxygenase 1
|
| Other Description |
FMO 1|Flavin-containing monooxygenase 1 (fetal liver)|dimethylaniline monooxygenase [N-oxide-forming] 1|dimethylaniline oxidase 1|fetal hepatic flavin-containing monooxygenase 1
|
| Swissprots |
A8K248 Q9UJC2 Q5QPT2 Q01740 B7Z3P4
|
| Accessions |
AAW56076 CCQ43165 EAW90892 EAW90893 EAW90894 EAW90895 Q01740 AK097039 AK290113 BAF82802 AK296198 BAH12280 AK315100 BAG37562 BC047129 AAH47129 BE465459 DA537896 DA750161 HQ257928 ADR82682 M64082 AAA52457 XM_005245037 XP_005245094 XM_005245038 XP_005245095 XM_006711241 XP_006711304 XM_006711242 XP_006711305 NM_001282692 NP_001269621 NM_001282693 NP_001269622 NM_001282694 NP_001269623 NM_002021 NP_002012
|
| Function |
This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenation of secondary and tertiary amines.
|
| Subcellular Location |
Microsome membrane. Endoplasmic reticulum membrane.
|
| Tissue Specificity |
Expressed mainly in fetal liver, adult kidney and, to a lesser extent, the intestine.
|
| Top Pathways |
Drug metabolism - cytochrome P450
|
