| Gene Symbol |
Arsb
|
| Entrez Gene |
11881
|
| Alt Symbol |
1110007C02Rik, AI480648, As-1, As-1r, As-1s, As-1t, As1, As1-r, As1-s, As1-t, Asr-1, Ast-1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
arylsulfatase B
|
| Other Description |
ASB|G4S|N-acetylgalactosamine-4-sulfatase|arylsulfatase B complex|arylsulfatase B regulation|arylsulfatase B structural|arylsulfatase B temporal regulation
|
| Swissprots |
Q3TYV7 Q3U4Q6 P50429 Q8C404 Q32KJ1
|
| Accessions |
EDL00926 P50429 AK003524 BAB22836 AK037155 AK083309 BAC38859 AK140163 AK154098 BAE32375 AK158312 BAE34455 AK189106 AK190270 AK191477 AK195452 AK195674 AK198200 AK205135 AK211718 AK212274 AK212990 BC055876 BC150661 AAI50662 BC168412 AAI68412 BN000746 CAI84992 M82877 AAA37261 X92096 CAA63067 XM_011244617 XP_011242919 NM_009712 NP_033842
|
| Function |
Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (By similarity). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (By similarity). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity). {ECO:0000250|UniProtKB:P15848, ECO:0000250|UniProtKB:P50430}.
|
| Subcellular Location |
Lysosome. Cell surface {ECO:0000269|PubMed:19536613}.
|
| Top Pathways |
Lysosome, Glycosaminoglycan degradation
|