ABCA2

Gene Symbol ABCA2
Entrez Gene 20
Alt Symbol ABC2
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family A (ABC1), member 2
Other Description ATP-binding cassette 2|ATP-binding cassette sub-family A member 2|ATP-binding cassette transporter 2|ATP-binding cassette, sub-family A, member 2
Swissprots Q76MW7 Q5W9G5 Q9HC28 A6NED5 Q9BZC7 Q5SPY5
Accessions AAK14335 EAW88331 EAW88332 EAW88333 Q9BZC7 AB028985 BAA83014 AB177854 BAD66832 AF178941 AAG09372 AF327657 AAK14334 AK295489 BAG58411 AK308738 AL162060 CAB82398 AL525193 AL833967 BC008755 AAH08755 BC029282 BC064542 AAH64542 BC090860 BC109244 AAI09245 BC144588 BC144589 BC172448 AAI72448 BE273611 BF516223 BF983101 BI195329 BM314339 BM474929 BM921242 BM921499 CD612070 CD676110 DB168116 JF279959 JF279960 U18235 AAA84436 U18236 AAA84437 XM_006716996 XP_006717059 XM_011518346 XP_011516648 NM_001606 NP_001597 NM_212533 NP_997698
Function Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development.
Subcellular Location Endosome membrane {ECO:0000269|PubMed:11309290}; Multi-pass membrane protein {ECO:0000269|PubMed:11309290}. Lysosome membrane {ECO:0000269|PubMed:11309290}; Multi-pass membrane protein {ECO:0000269|PubMed:11309290}. Note=Forms discrete, punctate intracellular vesicles.
Tissue Specificity Highly expressed in the brain, whereas lower levels of expression is observed in kidney and liver. {ECO:0000269|PubMed:11309290}.
Top Pathways ABC transporters, Lysosome

ABCA2 (N-19) - sc-48440 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ABCA2 (H-250) - sc-134559 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-ABCA2 antibody - ab91571 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ABCA2 antibody (ab91571) at 0.4 µg/mlLane 1 : 293T whole cell lysate at 50 µgLane 2 : 293T whole cell lysate at 15 µgLane 3 : 293T whole cell lysate at 5 µgdeveloped using the ECL technique

Anti-ABCA2 antibody - ab91569 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ABCA2 Antibody - LS-C92057 from LifeSpan Bioscience

Prices $415.00
Sizes 250 µg
Host Rat
Clonality Monoclonal

Anti-ABCA2 Antibody (PE) - LS-C124845 from LifeSpan Bioscience

Prices $355.00
Sizes 100 tst
Host Rat
Clonality Monoclonal

Anti-ABCA2 Antibody (FITC) - LS-C92058 from LifeSpan Bioscience

Host Rat
Clonality Monoclonal

Anti-ABCA2 Antibody (aa225-275) - LS-C289293 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCA2 Antibody (clone 9A2-51.3) - LS-C188370 from LifeSpan Bioscience

Prices $295.00
Sizes 250 µg
Host Rat
Clonality Monoclonal
Clone 9A2-51.3
Mouse ABCA2 transfected HeLa cells permeabilised then stained with Rat anti-Mouse ABCA2

Anti-ABCA2 Antibody (aa125-175) - LS-C289294 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCA2 Antibody (clone 9A2-51.3, RPE) - LS-C188372 from LifeSpan Bioscience

Prices $280.00
Sizes 100 tst
Host Rat
Clonality Monoclonal
Clone 9A2-51.3
Mouse ABCA2 transfected HeLa cells permeabilised and then stained with Rat anti-Mouse ABCA2:RPE

Anti-ABCA2 Antibody (aa96-145) - LS-C201449 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Jurkat. ABCA2 antibody dilution 1.0 ug/ml.

Anti-ABCA2 Antibody (aa2363-2376) IHC-plus™ - LS-B9197 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-ABCA2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

ABC2 Antibody - NBP1-87918 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: ABC2 Antibody [NBP1-87918] - Staining of human cell line U-251MG shows positivity in nucleus but not nucleoli.

ABCA2 Antibody - NBP1-30453 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunoprecipitation: ABCA2 Antibody [NBP1-30453] - Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from 293T cells. Antibodies: Affinity purified rabbit anti-ABCA2 antibodyNBP1-30453 used for IP at 10 mcg/mg lysate. ABCA2 was also immunoprecipitated by rabbit anti-ABCA2 antibodyNBP1-30452, which recognizes an upstream epitope.

ABCA2 Antibody - NBP1-30452 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ABCA2 Antibody [NBP1-30452] - Whole cell lysate from 293T cells. ABCA2 was also immunoprecipitated by rabbit anti-ABCA2 antibody NBP1-30453.

ABCA2 Antibody - NBP2-14249 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: ABCA2 Antibody [NBP2-14249] Staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells.

ABCA2 Antibody - NBP1-20863 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

ABCA2 Polyclonal Antibody - bs-6332R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ABC2 Polyclonal Antibody - bs-6515R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCA2 antibody produced in rabbit - SAB4301051 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCA2 antibody produced in rabbit - HPA042886 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ABCA2:<B>Cat. No. HPA042886</B>: Immunohistochemical staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells.

ABCA2 Antibody - N-terminal region (ARP43639_P050) - ARP43639_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ABCA2-Antibody-Center - AP21066a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysate from U-87 MG cell line, using ABCA2 Antibody (Center)(Cat. #AP21066a). AP21066a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.

ABCA2-Antibody-internal-region - AF2775a from Abgent, a WuXi AppTec company

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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