ATP6V0A4

Gene Symbol ATP6V0A4
Entrez Gene 50617
Alt Symbol A4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, STV1, VPH1, VPP2
Species Human
Gene Type protein-coding
Description ATPase, H+ transporting, lysosomal V0 subunit a4
Other Description ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 1B|ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 2 (38kD)|H(+)-transporting two-sector ATPase, noncatalytic accessory protein 1B|V-ATPase 116 kDa|V-type proton ATPase 116 kDa subunit a|V-type proton ATPase 116 kDa subunit a isoform 4|vacuolar proton pump 116 kDa accessory subunit|vacuolar proton pump, subunit 2|vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform
Swissprots Q32M47 A8KA80 A4D1R4 Q9HBG4
Accessions CBX47558 CBX47559 CBX47560 EAL24043 EAW83892 EAW83893 EAW83894 EAW83895 EAW83896 EAW83897 Q9HBG4 AF245517 AAG11415 AK055789 BAB71014 AK292945 BAF85634 BC109304 AAI09305 BC109305 AAI09306 DA857655 DB230144 XM_005250393 XP_005250450 XM_005250394 XP_005250451 NM_020632 NP_065683 NM_130840 NP_570855 NM_130841 NP_570856
Function Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney. {ECO:0000250}.
Subcellular Location Apical cell membrane; Multi-pass membrane protein. Note=Present at high density almost exclusively on the apical surface of alpha-intercalated cells in the cortical collecting ducts of the distal nephron.
Tissue Specificity Expressed in adult and fetal kidney. Found in the inner ear. {ECO:0000269|PubMed:12414817}.
Top Pathways Collecting duct acid secretion, Tuberculosis, Synaptic vesicle cycle, Rheumatoid arthritis, Phagosome

V-ATPase A4 (D-15) - sc-69096 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

V-ATPase A4 (V-14) - sc-69099 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ATP6V0A4 antibody - ab97440 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab97440 stained MALME-3M cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab97440 at 5µg/ml overnight at +4°C. The secondary antibody (pseudo-colored green) was Alexa Fluor® 488 goat anti- rabbit (ab150081) IgG (H+L) preadsorbed, used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (pseudo-colored red) at a 1/200 dilution for 1h at room temperature. DAPI was used to stain the cell nuclei (pseudo-colored blue) at a concentration of 1.43µM for 1hour at room temperature.

Anti-ATP6V0A4 antibody - ab55827 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ATP6V0A4 Antibody (C-Terminus) - LS-C46855 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ATP6V0A4 Antibody (aa242-271, AP) - LS-C252024 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP6V0A4 Antibody (aa242-271, APC) - LS-C252027 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP6V0A4 Antibody (aa242-271, Biotin) - LS-C252028 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP6V0A4 Antibody (aa242-271, FITC) - LS-C252029 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP6V0A4 Antibody (aa242-271, Azide-free, HRP) - LS-C252030 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP6V0A4 Antibody (aa242-271, PE) - LS-C252031 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP6V0A4 Antibody (aa242-271) - LS-C319705 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP6V0A4 Antibody (Internal) - LS-C345309 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of ATP6V0A4 Antibody with human HepG2 Whole Cell lysate.

Anti-ATP6V0A4 Antibody (aa242-271) - LS-C156666 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ATP6V0A4 Antibody western blot of CEM cell line lysates (35 ug/lane). The ATP6V0A4 antibody detected the ATP6V0A4 protein (arrow).

Anti-ATP6V0A4 Antibody (aa53-295) IHC-plus™ - LS-B10794 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-ATP6V0A4 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10794 concentration 7.5 ug/ml.

ATP6V0A4 Antibody - NBP1-32904 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATP6V0A4 Antibody - NBP2-39030 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: ATP6V0A4 Antibody [NBP2-39030] - Staining of human kidney shows strong cytoplasmic positivity in renal tubules.

ATP6V0A4 Antibody - NBP1-89330 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP6V0A4 antibody produced in rabbit - HPA018029 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ATP6V0A4: <B>Cat. No. HPA018029</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney shows strong cytoplasmic positivity in cells in tubules.

ANTI-ATP6V0A4 (CENTER) antibody produced in rabbit - SAB1303818 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ATP6V0A4 (Center): <B>Cat. No. SAB1303818</B>: ATP6V0A4 Antibody (Center)western blot analysis in CEM cell line lysates (35 μg/lane).

Anti-ATP6V0A4 antibody produced in rabbit - SAB2700444 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ATP6V0A4: <B>Cat. No. SAB2700444</B>: Western Blot analysis of atP6V0A4 in extracts from <B>Lanes</B><BR/>A. HepG2 using <B>Cat. No. SAB2700444</B> at a 1:3000 dilution.

ATP6V0A4 Antibody - middle region (ARP73760_P050) - ARP73760_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATP6V0A4 Antibody - middle region (OAAB02785) - OAAB02785 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

ATP6V0A4-Antibody-Center - AP5369c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
ATP6V0A4 Antibody (Center)(Cat. #AP5369c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ATP6V0A4 antibody detected the ATP6V0A4 protein (arrow).

ATP6V0A4 antibody - GTX110255 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-ATP6V0A4 antibody used in Western blot. GTX110255
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