PSMB4

Gene Symbol	PSMB4
Entrez Gene	5692
Alt Symbol	HN3, HsN3, PROS-26, PROS26
Species	Human
Gene Type	protein-coding
Description	proteasome (prosome, macropain) subunit, beta type, 4
Other Description	26 kDa prosomal protein|hsBPROS26|macropain beta chain|multicatalytic endopeptidase complex beta chain|proteasome beta chain|proteasome chain 3|proteasome subunit HsN3|proteasome subunit beta type-4|proteasome subunit, beta type, 4
Swissprots	P31148 Q6IBI4 Q969L6 B2R9L3 Q5SZS5 P28070
Accessions	EAW53442 P28070 AK294149 BAG57474 AK313825 BAG36560 BC000331 BC008314 BC010088 BC010098 BC011768 BC012168 BC017307 BC017451 BC017486 BT006917 AAP35563 CR456820 CAG33101 D26600 BAA05647 DQ890748 ABM81674 DQ892020 ABM82946 DQ895212 ABM86138 S71381 AAB31085 NM_002796 NP_002787
Function	The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal macrophage proteasome (By similarity). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. {ECO:0000250, ECO:0000269|PubMed:12097147}.
Subcellular Location	Cytoplasm {ECO:0000255|PROSITE- ProRule:PRU00809}. Nucleus {ECO:0000250}.
Top Pathways	Proteasome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Proteasome subunit beta type 4 full length protein - ab179855 from Abcam Category Protein Source Native Species Human

Human Proteasome subunit beta type 4 full length protein - ab115721 from Abcam Category Protein Source E. coli Species Human

PSMB4 Antibody Blocking Peptide - LS-E20502 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PSMB4 Antibody Blocking Peptide - LS-E27463 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PSMB4 Antibody Blocking Peptide - LS-E27462 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Proteasome subunit beta type 4 Recombinant Protein - H00005692-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Proteasome subunit beta type 4 Protein - NBP1-72545 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 50 µg, 250 µg Source E. coli Species Human

Recombinant human Proteasome subunit beta type-4 (OPCA00386) - OPCA00386 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human PROS26 protein - orb245078 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human PSMB4 protein - orb169096 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E. coli

PSMB4 Blocking Peptide - 33R-10173 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PSMB4 Blocking Peptide - 33R-8775 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PSMB4 protein (His tag) - 80R-2048 from Fitzgerald Category Protein Prices $365.00 Sizes 50 µg Source E.coli

Proteasome Subunit beta Type 4 Peptide - AC21-2286-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Proteasome Subunit beta Type 4 Peptide - AC21-2287-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PSMB4 / PROS26 (46-264, His-tag) - AR50131PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

PSMB4 / PROS26 (46-264, His-tag) - AR50131PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

PSMB4 / PROS26 - H00005692-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PSMB4 / PROS26 - H00005692-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PSMB4, 46-264aa, Human, His tag, E.coli - 01-2127-4 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

PSMB4 Peptide - 42-648P from ProSci Category Peptide Species Human, Mouse, Rat

PSMB4 Peptide - 42-830P from ProSci Category Peptide Species Human, Mouse

PSMB4 fusion protein - Ag1500 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

PSMB4 Human - ENPS-204 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human Proteasome Subunit Beta Type 4 Protein - BP002735-ENZ-197 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

Search more