Gene Symbol | Bak1 |
---|---|
Entrez Gene | 12018 |
Alt Symbol | Bak, N-BAK1, N-Bak |
Species | Mouse |
Gene Type | protein-coding |
Description | BCL2-antagonist/killer 1 |
Other Description | Bcl2 homologous antagonist/killer|apoptosis regulator BAK|bcl-2 homologous antagonist/killer |
Swissprots | O08734 E9QM21 Q8C264 |
Accessions | AAL01875 EDL22528 O08734 AF402617 AAL01876 AK089220 BAC40796 AK200878 AK211584 AW045927 BC057589 AAH57589 BY197389 CX564692 Y13231 CAA73684 XR_385266 NM_007523 NP_031549 |
Function | In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2. {ECO:0000250}. |
Subcellular Location | Mitochondrion membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Widely expressed. |
Top Pathways | Protein processing in endoplasmic reticulum, Viral carcinogenesis, MicroRNAs in cancer |