TNFRSF12A

Gene Symbol TNFRSF12A
Entrez Gene 51330
Alt Symbol CD266, FN14, TWEAKR
Species Human
Gene Type protein-coding
Description tumor necrosis factor receptor superfamily, member 12A
Other Description FGF-inducible 14|fibroblast growth factor-inducible immediate-early response protein 14|tumor necrosis factor receptor superfamily member 12A|tweak-receptor|type I transmembrane protein Fn14
Swissprots Q9NP84 Q9HCS0 D3DUA6
Accessions CAI54172 CAL48784 CCA61735 CCA61738 EAW85428 EAW85429 EAW85430 Q9NP84 AB035480 BAA94792 AB035481 BAB17850 AF191148 AAF69108 BC002718 AAH02718 BC020538 BC064377 BM842283 DQ892968 ABM83894 DQ896216 ABM87215 NM_016639 NP_057723
Function Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. {ECO:0000269|PubMed:11728344}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
Top Pathways Cytokine-cytokine receptor interaction

Fn14 CRISPR/Cas9 KO Plasmid (h) - sc-406156 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fn14 HDR Plasmid (h) - sc-406156-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fn14 Double Nickase Plasmid (h) - sc-406156-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fn14 Double Nickase Plasmid (h2) - sc-406156-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fn14 CRISPR Activation Plasmid (h) - sc-406156-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fn14 CRISPR Activation Plasmid (h2) - sc-406156-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fn14 Lentiviral Activation Particles (h) - sc-406156-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fn14 Lentiviral Activation Particles (h2) - sc-406156-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fn14 siRNA (h) - sc-43764 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Fn14 shRNA Plasmid (h) - sc-43764-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Fn14 shRNA (h) Lentiviral Particles - sc-43764-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TWEAK R/TNFRSF12 RNAi - H00051330-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU070071 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21744 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21744 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04976 from Sigma-Aldrich

Category miRNA

TNFRSF12A siRNA (Human) - CRH9704 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNFRSF12A - MBS8219711 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TNFRSF12A (NM_016639.2) - SHH431896 from Creative biogene

Category siRNA
Species Reactivities Human

TNFRSF12A shRNA Plasmid (Human) - CHH9704 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TNFRSF12A miRNA 3'UTR clone - MiUTR3H-08039 from Creative biogene

Species Reactivities Human
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