ACER1

Gene Symbol ACER1
Entrez Gene 125981
Alt Symbol ALKCDase1, ASAH3
Species Human
Gene Type protein-coding
Description alkaline ceramidase 1
Other Description N-acylsphingosine amidohydrolase (alkaline ceramidase) 3|N-acylsphingosine amidohydrolase 3|acylsphingosine deacylase 3|alkCDase 1|alkaline CDase 1
Swissprots Q8TDN7
Accessions EAW69104 EAW69105 Q8TDN7 AF347024 AAL83822 BC112122 AAI12123 BC112124 AAI12125 CU449837 HG510303 XM_011527673 XP_011525975 NM_133492 NP_597999
Function Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. Has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo- phytosphingosine or D-erythro-dihydrosphingosine as a backbone. May have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids (By similarity). {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity Mainly expressed in epidermis. {ECO:0000269|PubMed:16477081}.
Top Pathways Sphingolipid signaling pathway, Sphingolipid metabolism

ASAH3 (N-20) - sc-101848 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
ASAH3 (N-20): sc-101848. Western blot analysis of ASAH3 expression in A-431 (A), HeLa (B), K-562 (C), Jurkat (D), SK-MEL-28 (E) and A-375 (F) whole cell lysates.

Anti-ASAH3 antibody - ab99937 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ASAH3 antibody (ab99937) at 1/500 dilution + Human fetal lung lysate

Anti-ASAH3 antibody - ab113916 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ASAH3 antibody (ab113916) at 1 µg/ml + HCT15 cell lysate at 10 µg

Anti-ASAH3 antibody - ab55823 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ACER1 / ASAH3 Antibody (N-Terminus) - LS-C47019 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ACER1 / ASAH3 Antibody - LS-C137315 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ACER1 / ASAH3 Antibody (aa236-263, Biotin) - LS-C232363 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACER1 / ASAH3 Antibody (C-Terminus) - LS-C135889 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ACER1 / ASAH3 antibody LS-C135889 Western blot of Fetal Brain lysate. Antibody concentration 1 ug/ml.

Anti-ACER1 / ASAH3 Antibody (aa236-263, FITC) - LS-C232365 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACER1 / ASAH3 Antibody (aa141-190) - LS-C135888 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ACER1 / ASAH3 antibody LS-C135888 Western blot of HCT15 Cell lysate. Antibody concentration 1 ug/ml.

Anti-ACER1 / ASAH3 Antibody (aa236-263, Azide-free, HRP) - LS-C249364 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACER1 / ASAH3 Antibody (aa236-263, APC) - LS-C232364 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACER1 / ASAH3 Antibody (aa236-263, PE) - LS-C232366 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACER1 / ASAH3 Antibody - LS-C340938 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ACER1 / ASAH3 Antibody (aa236-263, AP) - LS-C232362 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACER1 / ASAH3 Antibody (aa235-264) - LS-C319277 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACER1 / ASAH3 Antibody (aa236-263) - LS-C160997 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ACER1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The ACER1 antibody detected the ACER1 protein (arrow).

ASAH3 Antibody - NBP1-90090 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ASAH3 Antibody [NBP1-90090] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY408822)

ASAH3 Antibody - NBP1-74083 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ASAH3 Antibody [NBP1-74083] - HCT15 Cell Lysate 1ug/ml Gel Concentration 12%

ASAH3 Antibody - NBP1-74125 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ASAH3 Antibody [NBP1-74125] - Human Fetal Brain Lysate, concentration 1 ug/ml.

Anti-ACER1 antibody produced in rabbit - SAB2107582 from Sigma-Aldrich

Prices $341.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ACER1: <B>Cat. No. SAB2107582</B>: Western blot analysis of ACER1 in Fetal Brain with ACER1 (alkaline ceramidase 1) antibody against the C terminal of ACER1 (50 μg) antibody at 1.0 μg/mL.

Anti-ACER1 antibody produced in rabbit - SAB2107581 from Sigma-Aldrich

Prices $341.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ACER1: <B>Cat. No. SAB2107581</B>: Western blot analysis of ACER1 in HCT15 with ACER1 (alkaline ceramidase 1) antibody against the C terminal of ACER1 (50 μg) antibody at 1.0 μg/mL.

Anti-ACER1 antibody produced in rabbit - HPA042506 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ACER1: <B>Cat. No. HPA042506</B>: Immunohistochemical staining of human prostate shows moderate cytoplasmic and membranous positivity in glandular cells.

ACER1 antibody - C-terminal region (ARP60812_P050) - ARP60812_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ACER1 antibody - C-terminal region (ARP60813_P050) - ARP60813_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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