PSMB6

Gene Symbol PSMB6
Entrez Gene 5694
Alt Symbol DELTA, LMPY, Y
Species Human
Gene Type protein-coding
Description proteasome (prosome, macropain) subunit, beta type, 6
Other Description PSY large multifunctional protease Y|macropain delta chain|multicatalytic endopeptidase complex delta chain|proteasome catalytic subunit 1|proteasome delta chain|proteasome subunit Y|proteasome subunit beta type-6|proteasome subunit delta
Swissprots Q96J55 P28072
Accessions EAW90407 P28072 AK311768 BAG34711 BC000835 AAH00835 BF671774 BM553399 BQ691763 BT009809 AAP88811 BU848746 CR457065 CAG33346 D29012 BAA06098 DQ891216 ABM82142 DQ894399 ABM85325 X61971 CAA43963 NM_001270481 NP_001257410 NM_002798 NP_002789
Function The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.
Subcellular Location Cytoplasm. Nucleus.
Top Pathways Proteasome

PSMB6 (E1K9O) Rabbit mAb - 13267 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone E1K9O
Western blot analysis of extracts from various cell lines using PSMB6 (E1K9O) Rabbit mAb.

PSMB6 (C-16) - sc-74868 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PSMB6 (H-49) - sc-292899 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

PSMB6 (T-20) - sc-74870 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PSMB6 (T-20): sc-74870. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing nuclear and cytoplasmic staining of cells in seminiferous ducts and Leydig cells.

PSMB6 (JQ-3) - sc-100455 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
PSMB6 (JQ-3): sc-100455. Western blot analysis of PSMB6 expression in SK-N-SH (A), HeLa (B) and SW-13 (C) whole cell lysates.

Anti-Proteasome 20S beta 6 antibody - ab3331 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence analysis of Proteasome 20S beta 6 (green) showing staining in the cytoplasm and nucleus of A431 cells (right) compared to a negative control without primary antibody (left). Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with ab3331 in 3% BSA-PBS at a dilution of 1:20 and incubated overnight at 4ºC in a humidified chamber. Cells were washed with PBST and incubated with a DyLight-conjugated secondary antibody in PBS at room temperature in the dark. F-actin (red) was stained with a flourescent red phalloidin and nuclei (blue) were stained with Hoechst or DAPI. Images were taken at a magnification of 60x.

Anti-Proteasome 20S beta 6 antibody - ab58079 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Proteasome 20S beta 6 antibody (ab58079) used in immunohistochemistry at 5ug/ml on formalin fixed and paraffin embedded human lymph node tissue.

Anti-Proteasome 20S beta 6 antibody - ab58081 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Proteasome 20S beta 6 antibody (ab58081) used in immunohistochemistry at 5ug/ml on formalin fixed and paraffin embedded human colon.

Anti-Proteasome 20S beta 6 antibody - ab94622 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Proteasome 20S beta 6 antibody (ab94622) at 1 µg/ml (in 5% skim milk / PBS buffer) + Jurkat cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Proteasome 20S beta 6 antibody [EPR9684] - ab150392 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9684
All lanes : Anti-Proteasome 20S beta 6 antibody [EPR9684] (ab150392) at 1/1000 dilutionLane 1 : Human fetal liver cell lysateLane 2 : NCI-H460 cell lysateLane 3 : Caco 2 cell lysateLane 4 : HeLa cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled Goat anti-Rabbit at 1/2000 dilution

Anti-Proteasome 20S beta 6 antibody [EPR9685] - ab150366 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9685
All lanes : Anti-Proteasome 20S beta 6 antibody [EPR9685] (ab150366) at 1/1000 dilutionLane 1 : Fetal liver lysateLane 2 : HeLa cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-PSMB6 Antibody (clone S51) - LS-C133415 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S51
Immunoperoxidase of monoclonal antibody to PSMB6 on formalin-fixed paraffin-embedded human colon. [antibody concentration 1 ug/ml]

Anti-PSMB6 Antibody - LS-C343799 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PSMB6 Antibody (aa35-84) - LS-C111926 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PSMB6 antibody LS-C111926 Western blot of Jurkat lysate.

Anti-PSMB6 Antibody (clone 2A3-5A8) - LS-C133414 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A3-5A8
Immunoperoxidase of monoclonal antibody to PSMB6 on formalin-fixed paraffin-embedded human lymph node tissue. [antibody concentration 1 ~10 ug/ml].

Proteasome 20S beta 6 Antibody (S51) - H00005694-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S51
Western Blot: Proteasome 20S beta 6 Antibody (S51) [H00005694-M02] - PSMB6 monoclonal antibody (M02), clone S51 Analysis of PSMB6 expression in A-431.

Proteasome 20S beta 6 Antibody - NBP1-56575 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Proteasome 20S beta 6 Antibody [NBP1-56575] - Jurkat cell lysate, concentration 0.2-1 ug/ml.

Proteasome 20S beta 6 Antibody (2A3-5A8) - H00005694-M01 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A3-5A8
Immunohistochemistry-Paraffin: Proteasome 20S beta 6 Antibody (2A3-5A8) [H00005694-M01] - Immunoperoxidase of monoclonal antibody to PSMB6 on formalin-fixed paraffin-embedded human lymph node tissue.

Proteasome 20S beta 6 Antibody - NBP1-88024 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Proteasome 20S beta 6 Antibody [NBP1-88024] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp.  Lane 4: Human plasma (IgG/HSA depleted).  Lane 5: Human liver tissue.  Lane 6: Human tonsil tissue

Proteasome 20S beta 6 Antibody - H00005694-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Monoclonal Anti-PSMB6 antibody produced in mouse - WH0005694M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A3-5A8
<B>Immunoblotting</B><BR/>Monoclonal Anti-PSMB6, <B>Cat. No. WH0005694M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~52.03 kDa using immunogen protein lysate.

Anti-PSMB6, (N-terminal) antibody produced in rabbit - SAB2104610 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PSMB6, antibody produced in rabbit: <B>Cat. No. SAB2104610</B>: Immunoblotting analysis of PSMB6 in Jurkat cell lysate with PSMB6 anitbody at 1 μg/mL.

Anti-PSMB6 (21-35) antibody produced in rabbit - SAB1100323 from Sigma-Aldrich

Prices $309.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-PSMB6 (21-35), <B>Cat. No. SAB1100323</B>: Immunofluorescence of HUVEC cells using Anti-PSMB6 (21-35), SAB1100323 (red), taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Monoclonal Anti-PSMB6 antibody produced in mouse - SAB1404264 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S51
<B>Immunohistochemistry</B><BR/>Monoclonal Anti-PSMB6: <B>Cat. No. SAB1404264</B>: Antibody concentration: 1 μg/mL using human colon tissue.

Anti-PSMB6 antibody produced in rabbit - HPA023312 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PSMB6: <B>Cat. No. HPA023312</B>: Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.
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