ABCD3

Gene Symbol ABCD3
Entrez Gene 5825
Alt Symbol ABC43, CBAS5, PMP70, PXMP1, ZWS2
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family D (ALD), member 3
Other Description 70 kDa peroxisomal membrane protein|ATP-binding cassette sub-family D member 3|Peroxisomal membrane protein-1 (70kD)|dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1))|peroxisomal membrane protein 1 (70kD, Zellweger syndrome)
Swissprots Q6NUN5 D3DT46 Q15271 P28288 Q9H529 Q96DA3
Accessions CAA58470 EAW73046 EAW73047 EAW73048 EAW73049 EAW73050 P28288 AK126440 AK296791 BAG59369 AK302714 BAG63934 AK308159 BC009712 AAH09712 BC068509 AAH68509 BT006644 AAP35290 BX648715 DC317792 M81182 AAA60128 X58528 CAA41416 XM_005271089 XP_005271146 XM_006710802 XP_006710865 XM_011541877 XP_011540179 NM_001122674 NP_001116146 NM_002858 NP_002849
Function Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity. {ECO:0000269|PubMed:11248239}.
Subcellular Location Peroxisome membrane {ECO:0000269|PubMed:10704444}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:10704444}.
Top Pathways ABC transporters, Peroxisome

ABCD3 (H-195) - sc-20973 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ABCD3 (H-195): sc-20973. Western blot analysis of ABCD3 expression in non-transfected: sc-110760 (A) and human ABCD3 transfected: sc-111305 (B) 293 whole cell lysates.

ABCD3 (N-20) - sc-21382 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ABCD3 (N-20): sc-21382. Western blot analysis of ABCD3 expression in HeLa whole cell lysate.

ABCD3 (C-20) - sc-21384 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PMP70 antibody - ab93016 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical staining of PMP70 in formalin fixed, paraffin embedded Human fetal liver showing membrane staining with ab93016 at a dilution of 1/100.

Anti-PMP70 antibody [EPR5614] - ab109448 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5614
All lanes : Anti-PMP70 antibody [EPR5614] (ab109448) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : SH SY5Y cell lysateLane 3 : Caco2 cell lysateLane 4 : HepG2 cell lysateLysates/proteins at 10 µg per lane.

Anti-PMP70 antibody [EPR5614] (Alexa Fluor® 488) - ab199018 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5614
Overlay histogram showing HeLa cells stained with ab199018 (red line). The cells were fixed with 4% formaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab199018, 1/500 dilution) for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) Alexa Fluor® 488 (ab199091) used at the same concentration and conditions as the primary antibody. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in HeLa cells fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-PMP70 antibody [EPR5614] (Alexa Fluor® 647) - ab199019 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5614
Overlay histogram showing HeLa cells stained with ab199019 (red line). The cells were fixed with 4% formaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab199019, 1/50 dilution) for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) Alexa Fluor® 647 (ab199093) used at the same concentration and conditions as the primary antibody. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a solid-state 25mW red diode laser (635 nm) and 675/30 bandpass filter. This antibody gave a positive signal in HeLa cells fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-PMP70 Antibody (aa644-659) - LS-C17322 from LifeSpan Bioscience

Prices $665.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PMP70 Antibody (aa644-659) - LS-C92001 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PMP70 Antibody - LS-C137430 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PMP70 Antibody (aa1-50) - LS-C288757 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PMP70 Antibody - LS-C342133 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PMP70 Antibody (clone 2H6) - LS-C198040 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2H6
Detection limit for recombinant GST tagged ABCD3 is 1 ng/ml as a capture antibody.

Anti-PMP70 Antibody (aa143-192) - LS-C110804 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ABCD3 / PMP70 antibody LS-C110804 Western blot of Fetal Small Intestine lysate.

Anti-PMP70 Antibody (aa526-539) IHC-plus™ - LS-B6476 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-ABCD3 / PMP70 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6476 concentration 2.5 ug/ml.

Anti-PMP70 Antibody (C-Terminus, clone EPR5614) IHC-plus™ - LS-B9367 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5614
Anti-PMP70 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-PMP70 Antibody (aa646-659) - LS-C313210 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
PMP70 antibody. IHC(P): Rat Brain Tissue.

Anti-PMP70 Antibody IHC-plus™ - LS-B11860 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

PMP70 Antibody (CL2524) - NBP2-36770 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Mouse
Clonality Monoclonal
Clone CL2524
Immunocytochemistry/Immunofluorescence: PMP70 Antibody (CL2524) [NBP2-36770] - Staining in U251 cell line showing specific staining of peroxisomes in green. Microtubule-staining and nuclear probes are visualized in red and blue respectively (where available). Antibody staining is shown in green.

PMP70 Antibody - NBP1-20871 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

PMP70 Antibody - NBP2-38199 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: PMP70 Antibody [NBP2-38199] - Immunofluorescent staining of human cell line A-431 shows positivity in vesicles.

PMP70 Antibody - NBP1-87258 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: PMP70 Antibody [NBP1-87258] - Staining of human cell line A-431 shows localization to peroxisomes.

PMP70 Antibody (2H6) - H00005825-M04 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2H6
Sandwich ELISA: PMP70 Antibody (2H6) [H00005825-M04] - Detection limit for recombinant GST tagged ABCD3 is 1 ng/ml as a capture antibody.

PXMP1 Polyclonal Antibody - bs-8584R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded human cervical carcinoma labeled with Anti-PXMP1/ABCD3/PMP70 Polyclonal Antibody, Unconjugated (bs-8584R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

Anti-PMP70 antibody produced in rabbit - P0497 from Sigma-Aldrich

Prices $364.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Mouse NIH3T3 cells were fixed and permeabilized with 3% paraformaldehyde followed by 0.5% Triton X-100. Fixed cells were stained with 1.5 μg/mL Anti-PMP70 (<B>Cat. No. P0497</B>) and developed with Goat Anti-Rabbit IgG, Cy3 conjugate.
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