| Gene Symbol | Hspa5 |
|---|---|
| Entrez Gene | 25617 |
| Alt Symbol | BIP, GRP78 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | heat shock protein 5 |
| Other Description | 78 kDa glucose-regulated protein|GRP 78|GRP-78|heat shock 70 kDa protein 5|heat shock 70kD protein 5|heat shock 70kDa protein 5 (glucose-regulated protein)|immunoglobulin heavy chain-binding protein|steroidogenesis-activator polypeptide |
| Swissprots | P06761 |
| Accessions | EDL93169 EDL93170 EDL93171 P06761 BC062017 AAH62017 CB327067 CB578015 FQ232006 M14050 AAA40817 NM_013083 NP_037215 |
| Function | Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate (By similarity). {ECO:0000250}. |
| Subcellular Location | Endoplasmic reticulum lumen. Melanosome {ECO:0000250}. Cytoplasm {ECO:0000250}. |
| Top Pathways | Protein export, Prion diseases, Protein processing in endoplasmic reticulum, Thyroid hormone synthesis, Antigen processing and presentation |
CompoZr® Knockout ZFN Kit - CKOZFN55243 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND55243 from Sigma-Aldrich
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HSPA5 siRNA (Rat) - CRR0819 from Cohesion Biosciences
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HSPA5 - MBS8218039 from MyBioSource
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shRNA set against Rat HSPA5 (NM_013083.2) - SHH315621 from Creative biogene
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GRP 78 siRNA (r) - sc-156167 from Santa Cruz Biotechnology
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GRP 78 shRNA Plasmid (r) - sc-156167-SH from Santa Cruz Biotechnology
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HSPA5 shRNA Plasmid (Rat) - CHR0819 from Cohesion Biosciences
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