PNP

Gene Symbol	PNP
Entrez Gene	4860
Alt Symbol	NP, PRO1837, PUNP
Species	Human
Gene Type	protein-coding
Description	purine nucleoside phosphorylase
Other Description	HEL-S-156an|epididymis secretory sperm binding protein Li 156an|inosine phosphorylase|inosine-guanosine phosphorylase|purine-nucleoside:orthophosphate ribosyltransferase
Swissprots	Q15160 B2R8S5 P00491 D3DS00 Q5PZ03
Accessions	AAA36460 AAV68044 EAW66458 EAW66459 P00491 AK098544 BAC05327 AK126154 AK307340 AK307364 AK313490 BAG36272 BC104206 AAI04207 BC104207 AAI04208 BC106074 AAI06075 BM193354 BU622706 CR407607 CAG28535 EU794649 ACJ13703 X00737 CAA25320 NM_000270 NP_000261
Function	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. {ECO:0000269|PubMed:2104852}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:22509282}.
Tissue Specificity	Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology. {ECO:0000269|PubMed:22509282}.
Top Pathways	Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Nucleoside phosphorylase full length protein - ab101210 from Abcam Category Protein Source E. coli Species Human

Mumps virus wild-type, Gloucester strain, nucleocapsid full length protein - ab74560 from Abcam Category Protein Source Saccharomyces cerevisiae

Nucleoside Phosphorylase / PNP Antibody Blocking Peptide - LS-E28056 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Nucleoside Phosphorylase / PNP Antibody Blocking Peptide - LS-E17536 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Purine Nucleoside Phosphorylase/PNP Partial Recombinant Protein - H00004860-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Purine Nucleoside Phosphorylase/PNP Recombinant Protein - H00004860-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Purine Nucleoside Phosphorylase/PNP Protein - NBP1-50872 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Recombinant Human PNP, CF - 6486-NP-010 from R&D Systems Category Protein Source E. coli-derived, Met1-Ser289, with a C-terminal 6-His tag

PNP Protein (OPPA02556) - OPPA02556 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Viral NP protein - orb244724 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Virus

HCoV-EMC/2012 NP protein (His Tag) - orb139405 from Biorbyt Category Protein Prices $357.00, $510.00, $808.00, $1,199.00 Sizes 5 μg, 20 μg, 50 μg, 100 μg Source Baculovirus-Insect Cells

Viral NP protein - orb244723 from Biorbyt Category Protein Prices $213.00, $408.00, $612.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 100 μg, 200 μg, 500 μg, 1 mg Species Virus

Viral NP protein - orb246095 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Virus

Viral NP protein - orb246094 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Virus

Human PNP His tag protein - orb84614 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 10 μg, 20 μg Source E. coli Species Human

Human PNP protein - orb169046 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Viral NP protein - orb244745 from Biorbyt Category Protein Prices $213.00, $408.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg Species Virus

H1N1 NP His tag protein - orb83615 from Biorbyt Category Protein Prices $357.00, $357.00, $510.00 Sizes 10 μg, 50 μg, 100 μg Source Insect

H7N9 NP protein (His Tag) - orb139406 from Biorbyt Category Protein Prices $281.00, $434.00, $646.00 Sizes 10 μg, 50 μg, 100 μg Source Baculovirus-Insect Cells

E.coli NP protein - orb244791 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg

H2N2 NP protein (His Tag) - orb139404 from Biorbyt Category Protein Prices $281.00, $323.00, $612.00 Sizes 10 μg, 20 μg, 50 μg Source Baculovirus-Insect Cells

Human PNP protein - orb244718 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

NP Blocking Peptide - 33R-3631 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PNP protein (His tag) - 80R-1547 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

Pancreatic Polypeptide Peptide - AC21-2926-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

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