POLR2F

Gene Symbol POLR2F
Entrez Gene 5435
Alt Symbol HRBP14.4, POLRF, RPABC14.4, RPABC2, RPB14.4, RPB6, RPC15
Species Human
Gene Type protein-coding
Description polymerase (RNA) II (DNA directed) polypeptide F
Other Description DNA-directed RNA polymerase II subunit F|DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide|DNA-directed RNA polymerases I, II, and III subunit RPABC2|RNA Polymerase II subunit 14.4 kD|RNA polymerases I, II, and III subunit ABC2
Swissprots P41584 Q6IAY3 P61218
Accessions CAA81629 EAW60202 EAW60203 P61218 AK026327 AK094034 AK098727 BAC05392 AK311128 AK311831 BAG34773 AL832562 BC003582 AAH03582 BP195499 BU160667 BU634038 CA396447 CR456546 CAG30432 CR457021 CAG33302 CU013146 CAK54577 CU013434 CAK54876 DA083933 DA203006 DA372532 DN989996 XM_011530235 XP_011528537 NM_001301129 NP_001288058 NM_001301130 NP_001288059 NM_001301131 NP_001288060 NM_021974 NP_068809 NR_125371
Function DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp element and together with parts of RPB1 and RPB2 forms a pocket to which the RPB4-RPB7 subcomplex binds (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:9852112}.
Top Pathways Huntington's disease, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Purine metabolism, RNA polymerase

Pol I/II/III RPB6 (B6-1) - sc-21751 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Pol I/II/III RPB6 (B6-1): sc-21751. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing nuclear localization.

Pol I/II/III RPB6 (E-15) - sc-32116 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Pol I/II/III RPB6 (V-17) - sc-32117 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pol I/II/III RPB6 (V-17): sc-32117. Western blot analysis of Pol I/II/III RPB6 expression in JEG-3 whole cell lysate.

Pol II RPB6 (E-8) - sc-271309 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Pol II RPB6 (E-8): sc-271309. Western blot analysis of Pol II RPB6 expression in HeLa nuclear extract (A) and SK-MEL-28 whole cell lysate (B).

Pol II RPB6 (FL-127) - sc-28711 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Pol II RPB6 (FL-127): sc-28711. Immunoperoxidase staining of formalin fixed, paraffin-embedded human urothelial cancer tissue showing nuclear staining of tumor cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Anti-POLR2F antibody - ab192482 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-POLR2F antibody [2780C3a] - ab51362 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2780C3a
Anti-POLR2F antibody [2780C3a] (ab51362) + immunizing peptide

Anti-POLR2F Antibody - LS-C75504 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-POLR2F Antibody (clone 2780C3a) - LS-C184406 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2780C3a

Anti-POLR2F Antibody - LS-C341713 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-POLR2F Antibody (clone 2780C3a) - LS-C342452 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2780C3a
Western blot analysis of immunized recombinant protein, using anti-POLR2F monoclonal antibody.

Anti-POLR2F Antibody - LS-C346051 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of HeLa cell using POLR2F antibody. Blue: DAPI for nuclear staining.

Anti-POLR2F Antibody (clone 2G2) - LS-C197945 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G2
Immunofluorescence of monoclonal antibody to POLR2F on HeLa cell . [antibody concentration 10 ug/ml]

POLR2F Antibody - NBP1-81714 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: POLR2F Antibody [NBP1-81714] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10 | Lane 2: Negative control (vector only transfected HEK293T lysate) | Lane 3: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells.

POLR2F Antibody (2G2) - H00005435-M02 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G2

Anti-POLR2F antibody produced in rabbit - HPA000827 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-POLR2F: <B>Cat. No. HPA000827</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human oral mucosa tissue showing nuclear staining of surface epithelial cells.

Rabbit anti-human DNA-directed RNA polymerases I, II, and III subunit RPABC2 (OACA01148) - OACA01148 from Aviva Systems Biology

Prices $270.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Rabbit anti-human DNA-directed RNA polymerases I, II, and III subunit RPABC2 (OACA01149) - OACA01149 from Aviva Systems Biology

Prices $270.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Rabbit anti-human DNA-directed RNA polymerases I, II, and III subunit RPABC2 (OACA01150) - OACA01150 from Aviva Systems Biology

Prices $270.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

POLR2F antibody - 10R-1369 from Fitzgerald

Prices $190.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2780C3a

POLR2F Polyclonal Antibody - A1824 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of mouse liver cells, using POLR2F antibody.

POLR2F antibody - 70R-19408 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

POLR2F Antibody - abx001507 from Abbexa

Host Rabbit
Clonality Polyclonal

POLR2F antibody - 15334-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human placenta tissue slide using 15334-1-AP( POLR2F Antibody) at dilution of 1:200 (under 10x lens)
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