ADRB1

Gene Symbol	ADRB1
Entrez Gene	153
Alt Symbol	ADRB1R, B1AR, BETA1AR, RHR
Species	Human
Gene Type	protein-coding
Description	adrenoceptor beta 1
Other Description	adrenergic, beta-1-, receptor|beta-1 adrenergic receptor|beta-1 adrenoceptor|beta-1 adrenoreceptor
Swissprots	P08588 Q9UKG7 B0LPE2 Q9UKG8 Q5T5Y4
Accessions	AAD53696 AAD53697 AAG40474 AAS66983 ABY87521 CAN37601 CBX55891 EAW49485 P08588 AF272890 BC169224 AAI69224 BC169225 AAI69225 BC169226 AAI69226 J03019 AAA51667 NM_000684 NP_000675
Function	Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. {ECO:0000269|PubMed:12391161}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Early endosome. Note=Colocalizes with RAPGEF2 at the plasma membrane (By similarity). Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression. {ECO:0000250}.
Top Pathways	cAMP signaling pathway, cGMP-PKG signaling pathway, Adrenergic signaling in cardiomyocytes, Salivary secretion, Dilated cardiomyopathy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

β 1 -AR siRNA (h) - sc-29580 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

β 1 -AR shRNA Plasmid (h) - sc-29580-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

β 1 -AR shRNA (h) Lentiviral Particles - sc-29580-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

beta-1 Adrenergic R/ADRB1 RNAi - H00000153-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU118531 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1776 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1776 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

ADRB1 siRNA (Human) - CRH0107 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ADRB1 - MBS8209544 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ADRB1 (NM_000684.2) - SHH232742 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ADRB1(NM_000684.2) - SHG043993 from Creative biogene Category siRNA Species Reactivities Human

Human beta 1 Adrenergic Receptor siRNA - orb260609 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ADRB1 shRNA Plasmid (Human) - CHH0107 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ADRB1 miRNA 3'UTR clone - MiUTR1H-00219 from Creative biogene Species Reactivities Human

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