| Gene Symbol |
TBX2
|
| Entrez Gene |
6909
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
T-box 2
|
| Other Description |
T-box protein 2|T-box transcription factor TBX2
|
| Swissprots |
Q13207 Q16424 Q7Z647
|
| Accessions |
EAW51424 EAW51425 EAW51426 Q13207 AB209378 BAD92615 AK001031 AK127429 AL832900 CAH10619 AW006595 BC052566 AAH52566 BC070054 BM985069 S81264 AAB36216 U28049 AAA73861 XM_011525158 XP_011523460 XM_011525159 XP_011523461 NM_005994 NP_005985
|
| Function |
Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation. Acts as a negative regulator of PML function in cellular senescence. May be required for cardiac atrioventricular canal formation. {ECO:0000269|PubMed:22002537}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00201}.
|
| Tissue Specificity |
Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary.
|