PDCD1

Gene Symbol PDCD1
Entrez Gene 5133
Alt Symbol CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1
Species Human
Gene Type protein-coding
Description programmed cell death 1
Other Description programmed cell death protein 1|protein PD-1|systemic lupus erythematosus susceptibility 2
Swissprots O00517 Q8IX89 Q15116
Accessions AAC41700 AAC51774 AAN64003 ABK41899 CBX51254 EAW71298 Q15116 AI928135 AK313848 BAG36577 AY206416 AAO25116 AY238517 AAO63583 AY322430 AAP85379 BC074740 AAH74740 CR988122 U64863 AAC51773 XM_006712573 XP_006712636 XM_006724986 XP_006725049 NM_005018 NP_005009
Function Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner. Possible cell death inducer, in association with other factors. {ECO:0000269|PubMed:21276005}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways T cell receptor signaling pathway, Cell adhesion molecules (CAMs)

Human PD1 gene - orb90964 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human

Cynomolgus Monkey PD-1 (NP_001271065) VersaClone cDNA - RDC1186 from R&D Systems

Prices $199.00
Sizes 10 µg
Species Monkey

Mouse PD-1 (NP_032824) VersaClone cDNA - RDC0893 from R&D Systems

Prices $199.00
Sizes 10 µg
Species Mouse

Human PD-1 (NP_005009) VersaClone cDNA - RDC0903 from R&D Systems

Prices $199.00
Sizes 10 µg
Species Human
The plasmid was transfected into 293H adherent cells with Sinofection reagent (Cat# STF01). After 48 h, Immunofluorescence staining of cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with Mouse anti-Flag Tag monoclonal antibody (CST#8146S) at 37℃ 1 hour. Then cells were stained with Goat Anti-mouse IgG secondary antibody. The fluorescent signal is detected by fluorescence microscope. Each expression experiment has negative control.

Human PD1 ORF clone(NM_005018.2) - CDCL185646 from Creative biogene

Species Human

Rat PD-1 (NP_001100397) VersaClone cDNA - RDC1908 from R&D Systems

Prices $199.00
Sizes 10 µg
Species Rat

Canine PD-1 (NP_001301026) VersaClone cDNA - RDC2098 from R&D Systems

Prices $199.00
Sizes 10 µg
Species Dog
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