| Gene Symbol |
SLC25A31
|
| Entrez Gene |
83447
|
| Alt Symbol |
AAC4, ANT4, SFEC35kDa
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
|
| Other Description |
ADP,ATP carrier protein 4|ADP/ATP translocase 4|ANT 4|adenine nucleotide translocase 4|adenine nucleotide translocator 4|solute carrier family 25 member 31|sperm flagellar energy carrier protein
|
| Swissprots |
Q9H0C2
|
| Accessions |
AAY40974 EAX05199 EAX05200 Q9H0C2 AJ863129 CAI05952 AL136857 CAB66791 AM393262 CAL38140 AY550240 AAT42263 BC022032 AAH22032 BG773445 XM_011532297 XP_011530599 XM_011532298 XP_011530600 NM_031291 NP_112581
|
| Function |
Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility. {ECO:0000269|PubMed:17137571}.
|
| Subcellular Location |
Mitochondrion inner membrane; Multi-pass membrane protein. Cell projection, cilium, flagellum. Note=In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region.
|
| Tissue Specificity |
Expressed in brain, liver, sperm and testis. {ECO:0000269|PubMed:15670820, ECO:0000269|PubMed:17137571}.
|
| Top Pathways |
Huntington's disease, Calcium signaling pathway, HTLV-I infection, cGMP-PKG signaling pathway
|
