| Gene Symbol |
Vldlr
|
| Entrez Gene |
25696
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
very low density lipoprotein receptor
|
| Other Description |
VLDL receptor|VLDL-R|very low-density lipoprotein receptor
|
| Swissprots |
P98166
|
| Accessions |
EDM13062 P98166 L35767 AAA42341 XM_006231197 XP_006231259 XM_006231198 XP_006231260 XM_006231199 XP_006231261 NM_013155 NP_037287
|
| Function |
Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein.
|
| Tissue Specificity |
Abundant in soleus, gastrocnemicus, heart muscle, placenta, brain, lung and white fat. Less in aorta, ovary, kidney, spleen, adrenal gland and thymus.
|