MPPE1

Gene Symbol MPPE1
Entrez Gene 65258
Alt Symbol PGAP5
Species Human
Gene Type protein-coding
Description metallophosphoesterase 1
Other Description metallo phosphoesterase|post-GPI attachment to proteins factor 5
Swissprots D3DUI7 B0YJ41 Q8TE26 Q8TAD6 Q8WZ32 B7WNJ3 D3DUI5 B0YJ40 Q9H958 B5ME53 Q53F39 Q9HAI4 Q9BU58 Q6GMP1 B0YJ39
Accessions AAM00277 AAM00278 ACA06017 ACA06018 ACA06019 EAX01561 EAX01562 EAX01563 EAX01564 EAX01565 EAX01566 EAX01567 EAX01568 EAX01569 EAX01570 EAX01571 EAX01572 Q53F39 AF289560 AAL55744 AF363484 AAM00279 AK021647 BAB13863 AK023052 BAB14378 AK054639 BAG51403 AK223450 BAD97170 AK309948 AL833636 AW663162 AX775853 CAE11626 BC002877 AAH02877 BC073994 AAH73994 BG701552 CR738004 DA581276 DB035278 DQ786245 XM_006722340 XP_006722403 XM_006722341 XP_006722404 XM_006722342 XP_006722405 XM_006722343 XP_006722406 XM_006722345 XP_006722408 XM_006722346 XP_006722409 XM_006722347 XP_006722410 XM_006722348 XP_006722411 XM_011525731 XP_011524033 XM_011525732 XP_011524034 XM_011525733 XP_011524035 XM_011525734 XP_011524036 XR_935068 NM_138608 NM_001242904 NP_001229833 NM_023075 NP_075563 NR_040241 NR_040242 NR_040243
Function Metallophosphoesterase required for transport of GPI- anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. {ECO:0000269|PubMed:19837036}.
Subcellular Location Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:19837036}; Multi-pass membrane protein {ECO:0000269|PubMed:19837036}. Golgi apparatus, cis-Golgi network membrane {ECO:0000269|PubMed:19837036}; Multi- pass membrane protein {ECO:0000269|PubMed:19837036}. Note=Also localizes to endoplasmic reticulum exit site.
Tissue Specificity Expressed in brain. {ECO:0000269|PubMed:11978971}.

MPPE1 CRISPR/Cas9 KO Plasmid (h) - sc-410109 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MPPE1 HDR Plasmid (h) - sc-410109-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MPPE1 Double Nickase Plasmid (h) - sc-410109-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MPPE1 Double Nickase Plasmid (h2) - sc-410109-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MPPE1 CRISPR Activation Plasmid (h) - sc-410109-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MPPE1 CRISPR Activation Plasmid (h2) - sc-410109-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MPPE1 Lentiviral Activation Particles (h) - sc-410109-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MPPE1 Lentiviral Activation Particles (h2) - sc-410109-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MPPE1 siRNA (h) - sc-75819 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MPPE1 shRNA Plasmid (h) - sc-75819-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MPPE1 shRNA (h) Lentiviral Particles - sc-75819-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU114951 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14509 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14509 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08119 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08119

MPPE1 siRNA (Human) - CRJ2197 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MPPE1 (NM_023075.5) - SHH344004 from Creative biogene

Category siRNA
Species Reactivities Human

MPPE1 shRNA Plasmid (Human) - CHJ2197 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MPPE1 miRNA 3'UTR clone - MiUTR3H-12200 from Creative biogene

Species Reactivities Human
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