NIPA1

Gene Symbol NIPA1
Entrez Gene 123606
Alt Symbol FSP3, SPG6
Species Human
Gene Type protein-coding
Description non imprinted in Prader-Willi/Angelman syndrome 1
Other Description magnesium transporter NIPA1|non-imprinted in Prader-Willi/Angelman syndrome 1|non-imprinted in Prader-Willi/Angelman syndrome region protein 1|spastic paraplegia 6 protein
Swissprots Q7KZB0 Q5HYA9 B2RA76 Q7RTP0 Q86XW4
Accessions CAH05585 CCO13782 EAW65549 EAW65550 EAW65551 Q7RTP0 AB089319 BAC67707 AK057846 AK314073 BAG36773 BC025678 AAH25678 BC103705 AAI03706 BC156247 AAI56248 BC172484 AAI72484 BK001020 DAA01477 BX648722 CAI45979 DQ891252 ABM82178 DQ894438 ABM85364 NM_001142275 NP_001135747 NM_144599 NP_653200
Function Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Early endosome {ECO:0000250}. Note=Recruited to the cell membrane in response to low extracellular magnesium. {ECO:0000250}.
Tissue Specificity Widely expressed with highest levels in neuronal tissues. {ECO:0000269|PubMed:14508710}.

Panoply™ Human NIPA1 Knockdown Stable Cell Line - CSC-DC010383 from Creative biogene

Category Cell Line
Species Human
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