Gene Symbol |
Slc7a2
|
Entrez Gene |
64554
|
Alt Symbol |
Cat2, Cat2a, Cat2b
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
|
Other Description |
CAT-2|cationic amino acid transporter 2|cationic amino acid transporter-2A|low affinity cationic amino acid transporter 2|solute carrier family 7, member 2
|
Swissprots |
B5D5P0 B5D5N9
|
Accessions |
AAY83364 B5D5N9 EDL78824 EDL78825 AF245001 AAQ14243 AF245002 AAQ14244 U53927 AAC52813 U53928 AAC52814 XM_008771281 XP_008769503 XM_008771282 XP_008769504 XM_008771283 XP_008769505 NM_001134686 NP_001128158 NM_022619 NP_072141
|
Function |
Functions as permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine). The affinity for its substrates differs between isoforms created by alternative splicing. May play a role in classical or alternative activation of macrophages via its role in arginine transport. {ECO:0000250|UniProtKB:P18581}.
|
Subcellular Location |
Cell membrane {ECO:0000250|UniProtKB:P18581}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P18581}.
|