MMP1

Gene Symbol MMP1
Entrez Gene 4312
Alt Symbol CLG, CLGN
Species Human
Gene Type protein-coding
Description matrix metallopeptidase 1
Other Description fibroblast collagenase|interstitial collagenase|matrix metallopeptidase 1 (interstitial collagenase)|matrix metalloprotease 1|matrix metalloproteinase 1
Swissprots P08156 P03956
Accessions AAA52033 AAB36941 AAV28732 CCQ43177 EAW67031 P03956 AK024818 AK098450 AK130687 AK223034 BAD96754 AK223035 BAD96755 AK223036 BAD96756 AK223056 BAD96776 AK223281 BAD97001 AK225495 AK297723 BAG60077 AK301340 BAG62888 BC013118 AAH13118 BC013875 AAH13875 BT006874 AAP35520 BT020147 AAV38949 DC385245 DQ399597 ABD92796 DQ890729 ABM81655 DQ893904 ABM84830 M13509 AAA35699 M15996 AAA35700 X05231 CAA28858 X54925 CAA38691 NM_001145938 NP_001139410 NM_002421 NP_002412
Function Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity. {ECO:0000269|PubMed:1645757}.
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000305|PubMed:2167156}.
Top Pathways Bladder cancer, PPAR signaling pathway, Rheumatoid arthritis

MMP-1 (3B6) - sc-21731 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MMP-1 (3B6): sc-21731. Western blot analysis of human recombinant MMP-1.

MMP-1 (C-18) - sc-6837 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MMP-1 (L-20) - sc-12348 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MMP-1 (SB12e) - sc-58377 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
MMP-1 (SB12e): sc-58377. Western blot analysis of human recombinant MMP-1.

MMP-1/8 (A-7) - sc-137044 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MMP-1/8 (A-7): sc-137044. Western blot analysis of MMP-8 expression in non-transfected: sc-117752 (A) and mouse MMP-8 transfected: sc-121696 (B) 293T whole cell lysates.

MMP-1/8 (H-300) - sc-30069 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MMP-1/8 (H-300): sc-30069. Western blot analysis of human recombinant MMP-1.

Anti-MMP1 antibody - ab38929 from Abcam

Prices $392.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP1 antibody (ab38929)Lane 1 : Human MMP1.Lane 2 : Cell Media from human chondrosarcoma (no treatment).Lane 3 : Cell Media from human chondrosarcoma (treated with TPA).

Anti-MMP1 antibody - ab137332 from Abcam

Prices $379.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue labelling MMP1, using ab137332 at a 1/250 dilution.

Anti-MMP1 antibody - ab168767 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP1 antibody (ab168767) at 1 µg/mlLane 1 : MMP1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-MMP1 antibody - ab28196 from Abcam

Prices $382.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP1 antibody (ab28196) at 1/1000 dilutionLane 1 : Human MMP 1Lane 2 : Cell media from human chondrosarcoma, untreated.Lane 3 : Cell media from human chondrosarcoma treated with TPA.

Anti-MMP1 antibody - ab4043 from Abcam

Prices $378.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human placenta tissue, staining MMP1 with ab4043.

Anti-MMP1 antibody - ab53142 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP1 antibody (ab53142) at 1/500 dilutionLane 1 : HepG2 cell extracts minus immunising peptideLane 2 : HepG2 cell extracts plus immunising peptide

Anti-MMP1 antibody - ab45014 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP1 antibody - ab118529 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Kidney tissue (formalin-fixed, paraffin-embedded) stained with ab118529 at 5 µg/ml followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-MMP1 antibody - ab38924 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Standard curve for MMP1 (Analyte: ab39297); dilution range 1pg/ml to 1µg/ml using Capture Antibody Mouse monoclonal [SB12e] to MMP1 - BSA and Azide free (ab25483) at 5µg/ml and Detector Antibody Rabbit polyclonal to MMP1 - Propeptide domain (ab38924) at 0.5µg/ml.

Anti-MMP1 antibody - ab89767 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-MMP1 antibody (ab89767) at 1 µg/ml + human pancreas tissue lysate at 50 µg

Anti-MMP1 antibody - ab38928 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP1 antibody (ab38928)Lane 1 : Human MMP1.Lane 2 : Cell Media from human chondrosarcoma (no treatment).Lane 3 : Cell Media from human chondrosarcoma (treated with TPA).

Anti-MMP1 antibody - ab11595 from Abcam

Prices $359.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP1 antibody [3A9.3] - ab38923 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3A9.3
All lanes : Anti-MMP1 antibody [3A9.3] (ab38923) at 1/1000 dilutionLane 1 : Human MMP 1Lane 2 : Cell media from neonatal human dermal fibroblasts treated with TNF alphaPerformed under reducing conditions.

Anti-MMP1 antibody [3B6] - ab2461 from Abcam

Prices $372.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone 3B6

Anti-MMP1 antibody [6A5] - ab119922 from Abcam

Prices $387.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6A5
ELISA image showing use of ab119922.

Anti-MMP1 antibody [AT4A5] - ab194228 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AT4A5
Anti-MMP1 antibody [AT4A5] (ab194228) at 1/1500 dilution + HaCaT cell lysate at 40 µgSecondarygoat anti-mouse secondary antibody conjugated to HRP

Anti-MMP1 antibody [EP1247Y] - ab52631 from Abcam

Prices $392.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1247Y
Anti-MMP1 antibody [EP1247Y] (ab52631) at 1/10000 dilution (unpurified) + MMP1 recombinant protein at 10 µgSecondaryPeroxidase-conjugated goat anti-rabbit IgG (H+L) at 1/1000 dilution

Anti-MMP1 antibody [EP1247Y] (Alexa Fluor® 488) - ab197233 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1247Y
ab197233 staining MMP1 in SKNSH cells. The cells were fixed with 4% formaldehyde (10 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab197233 at 1/100 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at 1/250 dilution (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).This product also gave a positive signal under the same testing conditions in SKNSH cells fixed with 100% methanol (5min).

Anti-MMP1 antibody [EP1247Y] (Alexa Fluor® 647) - ab196905 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1247Y
ab196905 staining MMP1 in SKNSH cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1%PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab196905 at 1/100 dilution (shown in red) and ab195887, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 488), at 1/250 dilution (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).This product also gave a positive signal under the same testing conditions in SKNSH cells fixed with 4% formaldehyde (10 min).
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