| Gene Symbol |
ASIC4
|
| Entrez Gene |
55515
|
| Alt Symbol |
ACCN4, BNAC4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
acid sensing (proton gated) ion channel family member 4
|
| Other Description |
acid-sensing (proton-gated) ion channel family member 4|acid-sensing ion channel 4|amiloride-sensitive cation channel 4, pituitary|amiloride-sensitive cation channel family member 4, pituitary|brain sodium channel 4
|
| Swissprots |
Q6PIN9 Q53SB7 Q9NQA4 Q6GMS1 Q96FT7
|
| Accessions |
AAY15054 CAB93980 CAC51338 EAW70760 EAW70761 EAW70762 EAW70763 Q96FT7 AK308804 AK309373 BC010439 AAH10439 BC031812 AAH31812 BC073912 DQ892104 ABM83030 EL736952 XM_005246671 XP_005246728 XM_011511438 XP_011509740 XM_011511439 XP_011509741 XM_011511440 XP_011509742 XM_011511441 XP_011509743 NM_182847 NP_878267 NM_018674
|
| Function |
Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. {ECO:0000269|PubMed:10852210}.
|
| Subcellular Location |
Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti. {ECO:0000269|PubMed:10852210}.
|
| Top Pathways |
Inflammatory mediator regulation of TRP channels
|
![Western Blot: ACCN4 Overexpression Lysate (Adult Normal) [NBL1-07233] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ACCN4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8699_ACCN4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07233-img0002.jpg)